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Erschienen in: Critical Care 5/2001

01.10.2001 | Commentary

Is succinylcholine appropriate or obsolete in the intensive care unit?

verfasst von: Leo HDJ Booij

Erschienen in: Critical Care | Ausgabe 5/2001

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Abstract

Muscle relaxants in intensive care unit (ICU) patients are predominantly administered to facilitate intubation. The adverse effect profile of succinylcholine is such that its use in the ICU must be considered obsolete. Suitable alternatives are the intermediately long-acting nondepolarizing relaxants, of which rocuronium is probably preferable.
Literatur
1.
Zurück zum Zitat Heckmatt JZ, Pitt MC, Kirkham F: Peripheral neuropathy and neuromuscular blockade presenting as prolonged respiratory paralysis following critical illness. Neuropediatrics 1993, 24: 123-125.CrossRefPubMed Heckmatt JZ, Pitt MC, Kirkham F: Peripheral neuropathy and neuromuscular blockade presenting as prolonged respiratory paralysis following critical illness. Neuropediatrics 1993, 24: 123-125.CrossRefPubMed
2.
Zurück zum Zitat Barohn RJ, Jackson CE, Rogers SJ, Ridings LW, McVey AL: Prolonged paralysis due to nondepolarising neuromuscular blocking agents and corticosteroids. Muscle Nerve 1994, 17: 647-654.CrossRefPubMed Barohn RJ, Jackson CE, Rogers SJ, Ridings LW, McVey AL: Prolonged paralysis due to nondepolarising neuromuscular blocking agents and corticosteroids. Muscle Nerve 1994, 17: 647-654.CrossRefPubMed
3.
Zurück zum Zitat Fiacchino F, Gemma M, Bricchi M, Giombini S, Regi B: Sensitivity to curare in patients with upper and lower motor neurone dysfunction. Anaesthesia 1991, 46: 980-982.CrossRefPubMed Fiacchino F, Gemma M, Bricchi M, Giombini S, Regi B: Sensitivity to curare in patients with upper and lower motor neurone dysfunction. Anaesthesia 1991, 46: 980-982.CrossRefPubMed
4.
Zurück zum Zitat Yentis SM: Suxamethonium and hyperkalaemia. Anaesth Intensive Care 1990, 18: 92-101.PubMed Yentis SM: Suxamethonium and hyperkalaemia. Anaesth Intensive Care 1990, 18: 92-101.PubMed
5.
Zurück zum Zitat Martyn JAJ, White DA, Gronert GA, Jaffe RS, Ward JM: Up-and down regulation of skeletal muscle acetylcholine receptors. Effects on neuromuscular blockers. Anesthesiology 1992, 72: 822-843. Martyn JAJ, White DA, Gronert GA, Jaffe RS, Ward JM: Up-and down regulation of skeletal muscle acetylcholine receptors. Effects on neuromuscular blockers. Anesthesiology 1992, 72: 822-843.
6.
Zurück zum Zitat Schwartz DE, Kelly B, Caldwell JE, Carlisle AS, Cohen NH: Succinylcholine-induced hyperkalemic arrest in a patient with severe metabolic acidosis and exsanguinating hemorrhage. Anesth Analg 1992, 75: 291-293.CrossRefPubMed Schwartz DE, Kelly B, Caldwell JE, Carlisle AS, Cohen NH: Succinylcholine-induced hyperkalemic arrest in a patient with severe metabolic acidosis and exsanguinating hemorrhage. Anesth Analg 1992, 75: 291-293.CrossRefPubMed
7.
Zurück zum Zitat Kindler GH, Verotta D, Gray AT, Gropper MA, Yost CS: Additive inhibition of nicotinic acetylcholine receptors by corticosteroids and the neuromuscular blocking drug vecuronium. Anesthesiology 2000, 92: 821-832. 10.1097/00000542-200003000-00026CrossRefPubMed Kindler GH, Verotta D, Gray AT, Gropper MA, Yost CS: Additive inhibition of nicotinic acetylcholine receptors by corticosteroids and the neuromuscular blocking drug vecuronium. Anesthesiology 2000, 92: 821-832. 10.1097/00000542-200003000-00026CrossRefPubMed
8.
Zurück zum Zitat Gronert GA: Cardiac arrest after succinylcholine. Mortality greater with rhabdomyolysis than receptor upregulation. Anesthesiology 2001, 94: 523-529. 10.1097/00000542-200103000-00026CrossRefPubMed Gronert GA: Cardiac arrest after succinylcholine. Mortality greater with rhabdomyolysis than receptor upregulation. Anesthesiology 2001, 94: 523-529. 10.1097/00000542-200103000-00026CrossRefPubMed
9.
Zurück zum Zitat Shearer ES, Russell GN: The effect of cardiopulmonary bypass on cholinesterase activity. Anaesthesia 1993, 48: 293-296.CrossRefPubMed Shearer ES, Russell GN: The effect of cardiopulmonary bypass on cholinesterase activity. Anaesthesia 1993, 48: 293-296.CrossRefPubMed
10.
Zurück zum Zitat Collard CD, Baker BW II, Johnson D, Bressler R, Harati Y: Cumulative reduction in serum cholinesterase following repeated therapeutic plasma exchange. J Clin Anesth 1996, 8: 44-48. 10.1016/0952-8180(95)00172-7CrossRefPubMed Collard CD, Baker BW II, Johnson D, Bressler R, Harati Y: Cumulative reduction in serum cholinesterase following repeated therapeutic plasma exchange. J Clin Anesth 1996, 8: 44-48. 10.1016/0952-8180(95)00172-7CrossRefPubMed
11.
Zurück zum Zitat Robson N, Robertson I, Whittaker M: Plasma cholinesterase changes in the puerperium. Anaesthesia 1986, 41: 243-249.CrossRefPubMed Robson N, Robertson I, Whittaker M: Plasma cholinesterase changes in the puerperium. Anaesthesia 1986, 41: 243-249.CrossRefPubMed
12.
Zurück zum Zitat Blanloeil Y, Delaroche O, Tequi B, Gunst JP, Dixneuf B: Prolonged apnea after suxamethonium administration during staphylococcal toxic shock [in French]. Ann Fr Anesth Reanim 1996, 15: 189-191. 10.1016/0750-7658(96)85041-6CrossRefPubMed Blanloeil Y, Delaroche O, Tequi B, Gunst JP, Dixneuf B: Prolonged apnea after suxamethonium administration during staphylococcal toxic shock [in French]. Ann Fr Anesth Reanim 1996, 15: 189-191. 10.1016/0750-7658(96)85041-6CrossRefPubMed
13.
Zurück zum Zitat Vanlinthout LEH, van Egmond J, De Boo T, Lerou JGC, Wevers RA, Booij LHDJ: Factors affecting magnitude and time course of neuromuscular block produced by suxamethonium. Br J Anaesth 1992, 69: 29-35.CrossRefPubMed Vanlinthout LEH, van Egmond J, De Boo T, Lerou JGC, Wevers RA, Booij LHDJ: Factors affecting magnitude and time course of neuromuscular block produced by suxamethonium. Br J Anaesth 1992, 69: 29-35.CrossRefPubMed
14.
Zurück zum Zitat Jensen ES, Viby-Mogensen J: Plasma cholinesterase and abnormal reaction to succinylcholine: twenty years experience with the Danish Cholinesterase research Unit. Acta Anaesthesiol Scand 1995, 39: 151-156.CrossRef Jensen ES, Viby-Mogensen J: Plasma cholinesterase and abnormal reaction to succinylcholine: twenty years experience with the Danish Cholinesterase research Unit. Acta Anaesthesiol Scand 1995, 39: 151-156.CrossRef
15.
Zurück zum Zitat Kelly RE, Dinner M, Turner LS, Haik B, Abramson DH, Daines P: Succinylcholine increased intraocular pressure in the human eye with the extraocular muscles detached. Anesthesiology 1993, 79: 948-952.CrossRefPubMed Kelly RE, Dinner M, Turner LS, Haik B, Abramson DH, Daines P: Succinylcholine increased intraocular pressure in the human eye with the extraocular muscles detached. Anesthesiology 1993, 79: 948-952.CrossRefPubMed
16.
Zurück zum Zitat Flynn PJ, Goldhill DR: Hemodynamic effects of neuromusuclar blocking agents. J Cardiothorac Anesth 1990, 4: 31-37.CrossRef Flynn PJ, Goldhill DR: Hemodynamic effects of neuromusuclar blocking agents. J Cardiothorac Anesth 1990, 4: 31-37.CrossRef
17.
Zurück zum Zitat Kopman AF, Klewicka MM, Kopman DJ, Neuman GG: Molar potency is predictive of the speed of onset of neuromuscular block for agents of intemediate, short, and ultrashort duration. Anesthesiology 1999, 90: 425-431. 10.1097/00000542-199902000-00016CrossRefPubMed Kopman AF, Klewicka MM, Kopman DJ, Neuman GG: Molar potency is predictive of the speed of onset of neuromuscular block for agents of intemediate, short, and ultrashort duration. Anesthesiology 1999, 90: 425-431. 10.1097/00000542-199902000-00016CrossRefPubMed
18.
Zurück zum Zitat Ostergaard D, Jensen FS, Jensen E, Viby-Mogensen J: Influence of plasma cholinesterase activity on recovery from mivacurium-induced neuromuscular blockade. Acta Anaesth Scand 1989, 33(suppl 191): 164. Ostergaard D, Jensen FS, Jensen E, Viby-Mogensen J: Influence of plasma cholinesterase activity on recovery from mivacurium-induced neuromuscular blockade. Acta Anaesth Scand 1989, 33(suppl 191): 164.
Metadaten
Titel
Is succinylcholine appropriate or obsolete in the intensive care unit?
verfasst von
Leo HDJ Booij
Publikationsdatum
01.10.2001
Verlag
BioMed Central
Erschienen in
Critical Care / Ausgabe 5/2001
Elektronische ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc1039

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