nach oben

Critical Care

Erschienen in:

Open Access 01.04.2014 | Editorial

Fluid therapy in patients with brain injury: what does physiology tell us?

verfasst von: Christian Ertmer, Hugo Van Aken

Erschienen in: Critical Care | Ausgabe 2/2014

Einloggen, um Zugang zu erhalten

Excerpt

The unique component of the cerebral circulation is the so called blood–brain barrier (BBB). The anatomical structures of the BBB consist of the cerebral vascular endothelial cells, the surrounding pericytes, the basal lamina and the perivascular astrocytes. These form the so-called neurovascular unit [1]. Notably, the endothelial cells are interconnected by tight junctions; thus, any solute transport will be transcellular, as opposed to paracellular, in the peripheral circulation [2]. The specific anatomy of the neurovascular unit allows the brain volume to be kept constant even in the context of marked changes in intravascular volume status. …

Daneman R: The blood–brain barrier in health and disease. Ann Neurol 2012, 72: 648-672. 10.1002/ana.23648CrossRefPubMed

Brightman MW, Reese TS: Junctions between intimately apposed cell membranes in the vertebrate brain. J Cell Biol 1969, 40: 648-677. 10.1083/jcb.40.3.648PubMedCentralCrossRefPubMed

Arieff AI, Llach F, Massry SG: Neurological manifestations and morbidity of hyponatremia: correlation with brain water and electrolytes. Medicine 1976, 55: 121-129. 10.1097/00005792-197603000-00002CrossRefPubMed

Melton JE, Patlak CS, Pettigrew KD, Cserr HF: Volume regulatory loss of Na, Cl, and K from rat brain during acute hyponatremia. Am J Physiol 1987, 252: F661-F669.PubMed

Lien YH, Shapiro JI, Chan L: Effects of hypernatremia on organic brain osmoles. J Clin Invest 1990, 85: 1427-1435. 10.1172/JCI114587PubMedCentralCrossRefPubMed

Sterns RH, Riggs JE, Schochet SS Jr: Osmotic demyelination syndrome following correction of hyponatremia. N Engl J Med 1986, 314: 1535-1542. 10.1056/NEJM198606123142402CrossRefPubMed

Lien YH, Shapiro JI, Chan L: Study of brain electrolytes and organic osmolytes during correction of chronic hyponatremia. Implications for the pathogenesis of central pontine myelinolysis. J Clin Invest 1991, 88: 303-309. 10.1172/JCI115292PubMedCentralCrossRefPubMed

Van Aken HK, Kampmeier TG, Ertmer C, Westphal M: Fluid resuscitation in patients with traumatic brain injury: what is a SAFE approach? Curr Opin Anaesthesiol 2012, 25: 563-565. 10.1097/ACO.0b013e3283572274CrossRefPubMed

Reid F, Lobo DN, Williams RN, Rowlands BJ, Allison SP: (Ab)normal saline and physiological Hartmann’s solution: a randomized double-blind crossover study. Clin Sci (Lond) 2003, 104: 17-24. 10.1042/CS20020202

10.

Shackford SR, Zhuang J, Schmoker J: Intravenous fluid tonicity: effect on intracranial pressure, cerebral blood flow, and cerebral oxygen delivery in focal brain injury. J Neurosurg 1992, 76: 91-98. 10.3171/jns.1992.76.1.0091CrossRefPubMed

11.

Ertmer C, Rehberg S, Van Aken H, Westphal M: Relevance of non-albumin colloids in intensive care medicine. Best Pract Res Clin Anaesthesiol 2009, 23: 193-212.CrossRefPubMed

12.

Ertmer C, Kampmeier T, Van Aken H: Fluid therapy in critical illness: a special focus on indication, the use of hydroxyethyl starch and its different raw materials. Curr Opin Anaesthesiol 2013, 26: 253-260.PubMed

13.

Rehm M, Orth V, Kreimeier U, Thiel M, Haller M, Brechtelsbauer H, Finsterer U: Changes in intravascular volume during acute normovolemic hemodilution and intraoperative retransfusion in patients with radical hysterectomy. Anesthesiology 2000, 92: 657-664. 10.1097/00000542-200003000-00008CrossRefPubMed

14.

Rehm M, Haller M, Orth V, Kreimeier U, Jacob M, Dressel H, Mayer S, Brechtelsbauer H, Finsterer U: Changes in blood volume and hematocrit during acute preoperative volume loading with 5% albumin or 6% hetastarch solutions in patients before radical hysterectomy. Anesthesiology 2001, 95: 849-856. 10.1097/00000542-200110000-00011CrossRefPubMed

15.

Finfer S, Bellomo R, Boyce N, French J, Myburgh J, Norton R: A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med 2004, 350: 2247-2256.CrossRefPubMed

16.

Myburgh J, Cooper DJ, Finfer S, Bellomo R, Norton R, Bishop N, Kai Lo S, Vallance S: Saline or albumin for fluid resuscitation in patients with traumatic brain injury. N Engl J Med 2007, 357: 874-884.CrossRefPubMed

17.

Reinhart K, Perner A, Sprung CL, Jaeschke R, Schortgen F, Johan Groeneveld AB, Beale R, Hartog CS: Consensus statement of the ESICM task force on colloid volume therapy in critically ill patients. Intensive Care Med 2012, 38: 368-383. 10.1007/s00134-012-2472-9CrossRefPubMed

18.

Myburgh JA, Mythen MG: Resuscitation fluids. N Engl J Med 2013, 369: 1243-1251. 10.1056/NEJMra1208627CrossRefPubMed

19.

Physioklin http://www.physioklin.de

Titel: Fluid therapy in patients with brain injury: what does physiology tell us?
verfasst von: Christian Ertmer
Hugo Van Aken
Publikationsdatum: 01.04.2014
Verlag: BioMed Central
Erschienen in: Critical Care / Ausgabe 2/2014
Elektronische ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc13764

Neu im Fachgebiet AINS

24.04.2024 | DGIM 2024 | Kongressbericht | Nachrichten

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

hier abonnieren

Springer Medizin

Fluid therapy in patients with brain injury: what does physiology tell us?

Excerpt

Neu im Fachgebiet AINS

Magen-Darm-Blutungen werden präklinisch oft falsch eingeschätzt

Sepsis-Verdacht: Eine Stunde, fünf essenzielle Maßnahmen

Hinter dieser Appendizitis steckte ein Erreger

Ärztliche Empathie hilft gegen Rückenschmerzen

Update AINS

Springer Medizin

Excerpt

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2014

Thoracic ultrasonography versus chest radiography for detection of pneumothoraces: challenges in deriving and interpreting summary diagnostic accuracy estimates

Protective mechanical ventilation in the non-injured lung: review and meta-analysis

Criticizing reporting standards fails to improve quality in animal research

Ventriculoarterial decoupling in human septic shock

Impact of compliance with infection management guidelines on outcome in patients with severe sepsis: a prospective observational multi-center study

Stress ulceration: prevalence, pathology and association with adverse outcomes

Neu im Fachgebiet AINS

Magen-Darm-Blutungen werden präklinisch oft falsch eingeschätzt

Sepsis-Verdacht: Eine Stunde, fünf essenzielle Maßnahmen

Hinter dieser Appendizitis steckte ein Erreger

Ärztliche Empathie hilft gegen Rückenschmerzen

Update AINS