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Erschienen in: Critical Care 1/2006

01.02.2005 | Commentary

Survival methods, including those using competing risk analysis, are not appropriate for intensive care unit outcome studies

verfasst von: David Schoenfeld

Erschienen in: Critical Care | Ausgabe 1/2006

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Abstract

The preferred analysis for studies of mortality among patients treated in an intensive care unit should compare the proportions of patients who died during hospitalization. Studies that look for prognostic covariates should use logistic regression. Survival methods, such as the proportional hazards model, or methods based on competing risk analysis are not appropriate because prolonged survival among patients that die during their hospitalization does not benefit the patient and, therefore, should not be measured in the statistical analysis.
Literatur
1.
Zurück zum Zitat Resche-Rigon M, Azoulay E, Chevret S: Evaluating mortality in intensive care units: contribution of competing risks analyses. Crit Care 2006, 10: R5. 10.1186/cc3921PubMedCentralCrossRefPubMed Resche-Rigon M, Azoulay E, Chevret S: Evaluating mortality in intensive care units: contribution of competing risks analyses. Crit Care 2006, 10: R5. 10.1186/cc3921PubMedCentralCrossRefPubMed
2.
Zurück zum Zitat Fine JP, Gray RJ: A proportional hazards model for the subdistri-bution of a competing risk. J Am Stat Assoc 1999, 94: 496-509. 10.2307/2670170CrossRef Fine JP, Gray RJ: A proportional hazards model for the subdistri-bution of a competing risk. J Am Stat Assoc 1999, 94: 496-509. 10.2307/2670170CrossRef
3.
Zurück zum Zitat Finkelstein DM, Schoenfeld DA: Analyzing survival in the presence of an auxiliary variable. Stat Med 1994, 13: 1747-1754.CrossRefPubMed Finkelstein DM, Schoenfeld DA: Analyzing survival in the presence of an auxiliary variable. Stat Med 1994, 13: 1747-1754.CrossRefPubMed
4.
Zurück zum Zitat Anonymous: Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome. Critical Care Med 2002, 30: 1-6.CrossRef Anonymous: Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome. Critical Care Med 2002, 30: 1-6.CrossRef
5.
Zurück zum Zitat Betensky RA, Schoenfeld DA: Nonparametric estimation in a cure model with random cure times. Biometrics 2001, 57: 282-286. 10.1111/j.0006-341X.2001.00282.xCrossRefPubMed Betensky RA, Schoenfeld DA: Nonparametric estimation in a cure model with random cure times. Biometrics 2001, 57: 282-286. 10.1111/j.0006-341X.2001.00282.xCrossRefPubMed
6.
Zurück zum Zitat Lagakos SW, Schoenfeld DA: Properties of proportional-hazards score tests under misspecified regression models. Biometrics 1984, 40: 1037-1048. 10.2307/2531154CrossRefPubMed Lagakos SW, Schoenfeld DA: Properties of proportional-hazards score tests under misspecified regression models. Biometrics 1984, 40: 1037-1048. 10.2307/2531154CrossRefPubMed
7.
Zurück zum Zitat Amato MBP, Barbas CSV, Medeiros DM, Magaldi RB, Schettino GP, Lorenzi-Filno G, Kairaila RA, Deheinzelin D, Munoz C, Taka-gaki TY: Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 1998, 338: 347-354. 10.1056/NEJM199802053380602CrossRefPubMed Amato MBP, Barbas CSV, Medeiros DM, Magaldi RB, Schettino GP, Lorenzi-Filno G, Kairaila RA, Deheinzelin D, Munoz C, Taka-gaki TY: Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 1998, 338: 347-354. 10.1056/NEJM199802053380602CrossRefPubMed
Metadaten
Titel
Survival methods, including those using competing risk analysis, are not appropriate for intensive care unit outcome studies
verfasst von
David Schoenfeld
Publikationsdatum
01.02.2005
Verlag
BioMed Central
Erschienen in
Critical Care / Ausgabe 1/2006
Elektronische ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc3949

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