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Erschienen in: Critical Care 3/2008

01.05.2008 | Review

Delirium in the intensive care unit

verfasst von: Timothy D Girard, Pratik P Pandharipande, E Wesley Ely

Erschienen in: Critical Care | Sonderheft 3/2008

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Abstract

Delirium, an acute and fluctuating disturbance of consciousness and cognition, is a common manifestation of acute brain dysfunction in critically ill patients, occurring in up to 80% of the sickest intensive care unit (ICU) populations. Critically ill patients are subject to numerous risk factors for delirium. Some of these, such as exposure to sedative and analgesic medications, may be modified to reduce risk. Although dysfunction of other organ systems continues to receive more clinical attention, delirium is now recognized to be a significant contributor to morbidity and mortality in the ICU, and it is recommended that all ICU patients be monitored using a validated delirium assessment instrument. Patients with delirium have longer hospital stays and lower 6-month survival than do patients without delirium, and preliminary research suggests that delirium may be associated with cognitive impairment that persists months to years after discharge. Little evidence exists regarding the prevention and treatment of delirium in the ICU, but multicomponent interventions reduce the incidence of delirium in non-ICU studies. Strategies for the prevention and treatment of ICU delirium are the subjects of multiple ongoing investigations.
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Zurück zum Zitat This article is part of Critical Care Volume 12 Supplement 3: Analgesia and sedation in the ICU. Publication of the supplement has been funded by an unrestricted grant from GlaxoSmithKline. GlaxoSmithKline has had no editorial control in respect of the articles contained in this publication.The opinions and views expressed in this publication are those of the authors and do not constitute the opinions or recommendations of the publisher or GlaxoSmithKline. Dosages, indications and methods of use for medicinal products referred to in this publication by the authors may reflect their research or clinical experience, or may be derived from professional literature or other sources. Such dosages, indications and methods of use may not reflect the prescribing information for such medicinal products and are not recommended by the publisher or GlaxoSmithKline. Prescribers should consult the prescribing information approved for use in their country before the prescription of any medicinal product.Whilst every effort is made by the publisher and editorial board to see that no inaccurate or misleading data, opinion, or statement appear in this publication, they wish to make it clear that the data and opinions appearing in the articles herein are the sole responsibility of the contributor concerned.Accordingly, the publishers, the editor and editorial board, GlaxoSmithKline, and their respective employees, officers and agents accept no liability whatsoever for the consequences of such inaccurate or misleading data, opinion or statement. This article is part of Critical Care Volume 12 Supplement 3: Analgesia and sedation in the ICU. Publication of the supplement has been funded by an unrestricted grant from GlaxoSmithKline. GlaxoSmithKline has had no editorial control in respect of the articles contained in this publication.The opinions and views expressed in this publication are those of the authors and do not constitute the opinions or recommendations of the publisher or GlaxoSmithKline. Dosages, indications and methods of use for medicinal products referred to in this publication by the authors may reflect their research or clinical experience, or may be derived from professional literature or other sources. Such dosages, indications and methods of use may not reflect the prescribing information for such medicinal products and are not recommended by the publisher or GlaxoSmithKline. Prescribers should consult the prescribing information approved for use in their country before the prescription of any medicinal product.Whilst every effort is made by the publisher and editorial board to see that no inaccurate or misleading data, opinion, or statement appear in this publication, they wish to make it clear that the data and opinions appearing in the articles herein are the sole responsibility of the contributor concerned.Accordingly, the publishers, the editor and editorial board, GlaxoSmithKline, and their respective employees, officers and agents accept no liability whatsoever for the consequences of such inaccurate or misleading data, opinion or statement.
Metadaten
Titel
Delirium in the intensive care unit
verfasst von
Timothy D Girard
Pratik P Pandharipande
E Wesley Ely
Publikationsdatum
01.05.2008
Verlag
BioMed Central
Erschienen in
Critical Care / Ausgabe Sonderheft 3/2008
Elektronische ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc6149

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