Background
Method
Study design and subject
Diagnosis of fatty pancreas
Laboratory tests
Statistical analyses
Results
Characteristics of the study subjects
Characteristic | Mean (SD) | N | % |
---|---|---|---|
Male gender | 720 | 68.3 | |
Age (years) | 43.1 ± 12.19 | ||
Age >35 years old | 723 | 68.6 | |
Body mass index (kg/m2) | 24.9 ± 3.96 | ||
Systolic blood pressure (mmHg) | 120 ± 37.2 | ||
Diastolic blood pressure (mmHg) | 75 ± 9.9 | ||
Fasting plasma glucose (mg/dL) | 96.7 ± 24.69 | ||
Triglyceride levels (mg/dL) | 127.1 ± 89.15 | ||
Total cholesterol levels (mg/dL) | 205.4 ± 59.0 | ||
LDL-cholesterol | 133.2 ± 35.29 | ||
HDL-cholesterol | 51.1 ± 12.87 | ||
NAFLD | |||
No | 516 | 49.0 | |
Yes | 538 | 51.0 |
Associations among metabolic risk factors and fatty liver
Risk Factor | Fatty pancreas | Odds ratio | p value | |
---|---|---|---|---|
Yes (n = 315) | No (n = 586) | (95 % CI) | (χ2) | |
Male sex (n = 574) | 228 (72.4 %) | 346 (59.0 %) | 1.818 (1.351–2.446) | <0.001 |
Age > 35 years (n = 612) | 268 (85.1 %) | 344 (58.7 %) | 4.011 (2.824–5.697) | <0.001 |
Systolic BP ≥ 130 mmHg (n = 201) | 99 (31.4 %) | 102 (17.4 %) | 2.175 (1.580–2.994) | <0.001 |
Diastolic BP ≥ 85 mmHg (n = 111) | 54 (17.1 %) | 57 (9.7 %) | 1.920 (1.286–2.866) | 0.001 |
Body mass index ≥ 25 kg/m2 (n = 390) | 206 (65.4 %) | 184 (31.4 %) | 4.129 (3.088–5.520) | <0.001 |
Type 2 diabetes mellitus (n = 62) | 31 (9.8 %) | 31 (5.3 %) | 1.954 (1.164–3.280) | 0.010 |
FPG ≥ 100 mg/dL (n = 187) | 99 (31.4 %) | 88 (15.0 %) | 2.594 (1.867–3.603) | <0.001 |
Triglycerides ≥ 150 mg/dL (n = 226) | 105 (33.3 %) | 121 (20.6 %) | 1.921 (1.412–2.615) | <0.001 |
Total cholesterol ≥ 200 mg/dL (n = 491) | 203 (64.4 %) | 288 (49.1 %) | 1.875 (1.415–2.486) | <0.001 |
LDL-C ≥ 100 mg/dL (n = 742) | 275 (87.3 %) | 467 (79.7 %) | 1.752 (1.189–2.582) | 0.004 |
HDL-C < 40 (M) or < 50 (F) mg/dL (n = 194) | 86 (27.3 %) | 108 (18.4 %) | 1.662 (1.202–2.298) | 0.002 |
Association between fatty pancreas and fatty liver
Association between fatty pancreas and diabetes mellitus
Discussion
Characteristics of the study subjects
Association between fatty pancreeas and metabolic risk factors
Risk factor | β | SE (β) | β/SE | ORadj | 95 % CI | p value |
---|---|---|---|---|---|---|
Age > 35 years | 1.077 | 0.191 | 5.639 | 2.936 | 2.020–4.267 | <0.001 |
BMI ≥ 25 kg/m2 | 1.261 | 0.154 | 8.188 | 3.529 | 2.607–4.775 | <0.001 |
FPG ≥ 100 mg/dL | 0.531 | 0.183 | 2.902 | 1.701 | 1.189–2.434 | 0.004 |
Total cholesterol ≥ 200 mg/dL | 0.491 | 0.157 | 3.127 | 1.634 | 1.201–2.223 | <0.001 |
Constant | −2.423 |