Background
Methods
Study population
Data collection
Statistical analysis
Results
Measured outcome | Sphere | Cylinder | MRSE |
J
180
|
J
45
| UDVA | CDVA | K steep
| K flat
| K average
| CCT |
---|---|---|---|---|---|---|---|---|---|---|---|
Preop | −2.5 ± 2.5 | −3.22 ± 0.59 | −4.12 ± 2.55 | −0.16 ± 0.92 | −0.26 ± 1.36 | −0.94 ± 0.35 | +0.01 ± 0.09 | 44.80 ± 1.56 | 42.16 ± 1.49 | 43.48 ± 1.47 | 547.00 ± 21.65 |
Postop | +0.04 ± 0.48 | −0.72 ± 0.46 | −0.31 ± 0.56 | −0.03 ± 0.25 | −0.02 ± 0.35 | −0.04 ± 0.07 | −0.00 ± 0.02 | 39.97 ± 2.18 | 39.06 ± 2.01 | 39.51 ± 2.08 | 464.20 ± 48.07 |
Post-Pre | +2.55 ± 2.65 | +2.52 ± 0.69 | +3.82 ± 2.82 | +0.13 ± 0.94 | +0.27 ± 1.39 | +0.90 ± 0.35 | −0.01 ± 0.09 | −4.83 ± 2.36 | −3.11 ± 1.93 | −3.97 ± 2.12 | −82.74 ± 41.45 |
P value
|
<0.0001
|
<0.0001
|
<0.0001
|
0.51
|
0.35
|
<0.0001
|
0.48
|
<0.0001
|
<0.0001
|
<0.0001
|
<0.0001
|
Efficacy & safety
Predictability
Keratometry and central corneal thickness changes
Changes in higher-order aberrations
Measured outcome | Coma | Trefoil | Spherical Aberration | Secondary Astigmatism | HOA root- mean-square |
---|---|---|---|---|---|
Preoperative | 0.22 ± 0.11 | 0.11 ± 0.07 | 0.18 ± 0.07 | 0.04 ± 0.03 | 0.47 ± 0.11 |
Postoperative | 0.31 ± 0.18 | 0.16 ± 0.10 | 0.33 ± 0.19 | 0.21 ± 0.09 | 0.77 ± 0.27 |
p-value | 0.07 | 0.047 | 0.004 | <0.0001 | <0.0001 |
Change (Δ) in higher-order aberrations | Mean Diff. | 95 % CI of diff. | Significant? |
---|---|---|---|
Δ Coma vs. Δ Trefoil | +0.03 | −0.13 to 0.20 | No |
Δ Coma vs Δ Spherical Aberration | −0.06 | −0.23 to 0.11 | No |
Δ Coma vs Δ Secondary Astigmatism | −0.08 | −0.25 to 0.09 | No |
Δ coma vs. Δ HOA root-mean-square | −0.22 | −0.38 to −0.05 | Yes |
Δ Trefoil vs Δ Spherical Aberration | −0.09 | −0.26 to 0.07 | No |
Δ Trefoil vs. Δ Secondary Astigmatism | −0.12 | −0.28 to 0.05 | No |
Δ Trefoil vs. Δ HOA root-mean-square | −0.25 | −0.42 to −0.08 | Yes |
Δ Spherical Aberration vs. Δ Secondary Astigmatism | −0.02 | −0.19 to 0.14 | No |
Δ Spherical Aberration vs Δ HOA root-mean-square | −0.16 | −0.32 to 0.01 | No |
Δ Secondary Astigmatism vs. Δ HOA root-mean-square | −0.14 | −0.30 to 0.03 | No |
Pearson r | Coma (Post-Pre) | Trefoil (Post-Pre) | SA (Post-Pre) | Sec Astig (Post-Pre) | RMS (Post-Pre) |
---|---|---|---|---|---|
MSER | −0.13 (−0.52 to +0.30) | −0.16 (−0.54 to +0.27) | −0.57 (−0.80 to −0.21) | −0.32 (−0.65 to 0.11) | −0.43 (−0.72 to −0.02) |
p-value |
0.55
|
0.46
|
0.004
|
0.14
|
0.04
|
Astigmatism | −0.18 (−0.55 to 0.25) | −0.36 (−0.67 to 0.06) | −0.08 (−0.48 to 0.34) | −0.38 (−0.69 to 0.03) | −0.31 (−0.64 to 0.12) |
p-value |
0.41
|
0.09
|
0.72
|
0.07
|
0.15
|