Background
Methods
Data sources used for analysis
ART prescription data (APD)
The German ClinSurv HIV cohort (CSH)
Combination of data sources
Determining the number of people living with HIV receiving ART
Results
ClinSurv HIV cohort (CSH)
Year/quarter | Patients under observation | Patients under ART time | Observation time | Time under ART or interruption | ART status unknown | Art naive | ART regimens with approved drugs exclusively | ART regimens containing non-approved drugs | Treatment interruptions | ART experienced | TCMs in the CSH | Proportion of interruptions |
---|---|---|---|---|---|---|---|---|---|---|---|---|
N
|
Days
| |||||||||||
2006/I
| 8717 | 6986 | 753553 | 613673 | 8211 | 131728 | 516827 | 29909 | 66937 | 81.4% | 84.5% | 10.9% |
2006/II
| 8856 | 7104 | 773115 | 630625 | 7907 | 134629 | 533732 | 32431 | 64462 | 81.6% | 85.3% | 10.2% |
2006/III
| 9002 | 7214 | 792169 | 646716 | 7742 | 137766 | 547485 | 36102 | 63129 | 81.6% | 86.2% | 9.8% |
2006/IV
| 9075 | 7281 | 803312 | 655415 | 7530 | 140415 | 558719 | 36453 | 60243 | 81.6% | 87.0% | 9.2% |
2007/I
| 9267 | 7434 | 798257 | 652832 | 7219 | 138281 | 560733 | 33462 | 58637 | 81.8% | 87.7% | 9.0% |
2007/II
| 9407 | 7552 | 820040 | 671081 | 7345 | 141682 | 579930 | 33382 | 57769 | 81.8% | 88.4% | 8.6% |
2007/III
| 9564 | 7689 | 844690 | 690514 | 7304 | 146945 | 595635 | 38313 | 56566 | 81.7% | 89.1% | 8.2% |
2007/IV
| 9683 | 7828 | 855138 | 704369 | 6948 | 143877 | 609239 | 39403 | 55727 | 82.4% | 89.5% | 7.9% |
2008/I
| 9758 | 7937 | 853480 | 705518 | 6344 | 141676 | 619880 | 31297 | 54341 | 82.7% | 89.8% | 7.7% |
2008/II
| 9903 | 8069 | 863850 | 716324 | 5985 | 141595 | 632750 | 31325 | 52249 | 82.9% | 90.4% | 7.3% |
2008/III
| 10031 | 8206 | 884551 | 737289 | 5895 | 141423 | 656479 | 28383 | 52427 | 83.4% | 90.7% | 7.1% |
2008/IV
| 10124 | 8340 | 896771 | 752357 | 5982 | 138495 | 678973 | 22195 | 51189 | 83.9% | 91.0% | 6.8% |
2009/I
| 10222 | 8484 | 886182 | 747140 | 5303 | 133792 | 677700 | 21820 | 47620 | 84.3% | 91.3% | 6.4% |
2009/II
| 10384 | 8624 | 910943 | 769502 | 4859 | 136659 | 700526 | 21972 | 47004 | 84.5% | 91.6% | 6.1% |
2009/III
| 10569 | 8814 | 934456 | 791390 | 4779 | 138362 | 722970 | 22322 | 46098 | 84.7% | 91.8% | 5.8% |
2009/IV
| 10697 | 8989 | 946177 | 808947 | 4660 | 132635 | 742278 | 22853 | 43816 | 85.5% | 92.0% | 5.4% |
2010/I
| 10799 | 9140 | 936276 | 805104 | 4473 | 126765 | 741693 | 22313 | 41098 | 86.0% | 92.3% | 5.1% |
2010/II
| 10956 | 9290 | 958828 | 827947 | 4376 | 126573 | 768583 | 21791 | 37573 | 86.3% | 92.4% | 4.5% |
2010/III
| 11123 | 9468 | 980925 | 849665 | 4289 | 127041 | 792663 | 21195 | 35807 | 86.6% | 92.4% | 4.2% |
2010/IV
| 11171 | 9617 | 989771 | 865271 | 3898 | 120674 | 808229 | 22985 | 34057 | 87.4% | 92.3% | 3.9% |
2011/I
| 11258 | 9761 | 974608 | 859468 | 3418 | 111790 | 803378 | 24123 | 31967 | 88.2% | 92.3% | 3.7% |
2011/II
| 11333 | 9870 | 994656 | 880602 | 3347 | 110776 | 824465 | 25470 | 30667 | 88.5% | 92.3% | 3.5% |
2011/III
| 11467 | 10030 | 1013429 | 901100 | 3305 | 109118 | 845603 | 26049 | 29448 | 88.9% | 92.4% | 3.3% |
2011/IV
| 11480 | 10089 | 1021398 | 910156 | 3063 | 108245 | 857736 | 24301 | 28119 | 89.1% | 92.5% | 3.1% |
2012/I
| 11588 | 10196 | 1014121 | 906295 | 3068 | 104831 | 858296 | 21730 | 26269 | 89.4% | 92.6% | 2.9% |
2012/II
| 11612 | 10261 | 1019125 | 914177 | 2916 | 102114 | 867192 | 20862 | 26123 | 89.7% | 92.6% | 2.9% |
2012/III
| 11651 | 10338 | 1032814 | 929619 | 2661 | 100626 | 883234 | 21460 | 24925 | 90.0% | 92.4% | 2.7% |
2012/IV
| 11574 | 10334 | 1023954 | 925347 | 2423 | 96245 | 882817 | 20421 | 22109 | 90.4% | 92.5% | 2.4% |
2013/I
| 11428 | 10229 | 980141 | 890397 | 2109 | 87707 | 852262 | 18571 | 19564 | 90.8% | 92.7% | 2.2% |
2013/II
| 11092 | 9978 | 960764 | 876969 | 1508 | 82345 | 843148 | 16594 | 17227 | 91.3% | 92.8% | 2.0% |
2103/III
| 10760 | 9725 | 879002 | 804520 | 1199 | 73313 | 775500 | 14296 | 14724 | 91.5% | 92.7% | 1.8% |
2013/IV
| 8358 | 7610 | 363973 | 331301 | 621 | 31848 | 317585 | 7227 | 6489 | 91.0% | 92.5% | 2.0% |
Antiretroviral prescription data (APD)
Year/quarter | German population | Number of people in SHI | SHI-coverage nationwide | Weighted SHI-coverage factor |
---|---|---|---|---|
2006/I
| 82314906 | 70013157 | 85.1% | 83.2% |
2007/I
| 82217837 | 70022112 | 85.2% | 83.5% |
2008/I
| 82002356 | 69952132 | 85.3% | 83.4% |
2009/I
| 81802257 | 69719142 | 85.2% | 84.1% |
2010/I
| 81751602 | 69473638 | 85.0% | 84.3% |
2011/I
| 81843743 | 69311329 | 84.7% | 83.3% |
2012/I
| 81843743* | 69398840 | 84.8% | 83.9% |
2013/I
| 81843743* | 69521912 | 84.9% | 84.0% |
Determining the number of people living with HIV receiving ART
Year/quarter | Days per quarter | DDDs of TCM from APD | Persons receiving SHI-covered TCM | Weighted SHI-coverage factor | People living with HIV treated with TCM | TCMs in the CSH | People living with HIV receiving ART in Germany | Proportion of interruptions in the CSH | HIV-infected people with ART experience in Germany (PT_E) | PT_E statistically smoothed | 95% CI | 95% CI | PT_E smoothed and rounded N (95% CI) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2006/I
| 90 | 1778070 | 19756 | 83.2% | 23751 | 84.5% | 28101 | 10.9% | 31547 | 31505 | 30796 | 32229 | 31500 (31000-32000) |
2006/II
| 91 | 1910070 | 20990 | 83.2% | 25222 | 85.3% | 29586 | 10.2% | 32953 | 32198 | 31559 | 32848 | 32000 (31500-33000) |
2006/III
| 92 | 1975770 | 21476 | 83.1% | 25824 | 86.2% | 29960 | 9.8% | 33203 | 32896 | 32321 | 33480 | 33000 (32500-33500) |
2006/IV
| 92 | 2114310 | 22982 | 83.1% | 27641 | 87.0% | 31757 | 9.2% | 34971 | 33600 | 33082 | 34125 | 33500 (33000-34000) |
2007/I
| 90 | 1982490 | 22028 | 83.5% | 26385 | 87.7% | 30092 | 9.0% | 33064 | 34310 | 33838 | 34787 | 34500 (34000-35000) |
2007/II
| 91 | 2106480 | 23148 | 83.3% | 27776 | 88.4% | 31434 | 8.6% | 34396 | 35024 | 34588 | 35465 | 35000 (34500-35500) |
2007/III
| 92 | 2174850 | 23640 | 83.3% | 28383 | 89.1% | 31844 | 8.2% | 34687 | 35743 | 35330 | 36159 | 35500 (35500-36000) |
2007/IV
| 92 | 2326950 | 25293 | 83.3% | 30377 | 89.5% | 33926 | 7.9% | 36841 | 36467 | 36066 | 36872 | 36500 (36000-37000) |
2008/I
| 91 | 2204460 | 24225 | 83.4% | 29023 | 89.8% | 32312 | 7.7% | 35009 | 37195 | 36794 | 37600 | 37000 (37000-37500) |
2008/II
| 91 | 2418270 | 26574 | 83.5% | 31814 | 90.4% | 35196 | 7.3% | 37964 | 37926 | 37516 | 38339 | 38000 (37500-38500) |
2008/III
| 92 | 2498580 | 27158 | 84.3% | 32211 | 90.7% | 35508 | 7.1% | 38226 | 38661 | 38237 | 39089 | 38500 (38000-39000) |
2008/IV
| 92 | 2680710 | 29138 | 84.2% | 34578 | 91.0% | 38009 | 6.8% | 40781 | 39399 | 38957 | 39845 | 39500 (39000-40000) |
2009/I
| 90 | 2562540 | 28473 | 84.1% | 33844 | 91.3% | 37072 | 6.4% | 39595 | 40139 | 39678 | 40604 | 40000 (39500-40500) |
2009/II
| 91 | 2719650 | 29886 | 84.1% | 35529 | 91.6% | 38809 | 6.1% | 41336 | 40882 | 40403 | 41366 | 41000 (40500-41500) |
2009/III
| 92 | 2792580 | 30354 | 84.3% | 36015 | 91.8% | 39239 | 5.8% | 41667 | 41627 | 41132 | 42127 | 41500 (41000-42000) |
2009/IV
| 92 | 2980560 | 32397 | 84.0% | 38544 | 92.0% | 41876 | 5.4% | 44274 | 42374 | 41866 | 42887 | 42500 (42000-43000) |
2010/I
| 90 | 2829630 | 31440 | 84.3% | 37290 | 92.3% | 40385 | 5.1% | 42556 | 43121 | 42605 | 43643 | 43000 (42500-43500) |
2010/II
| 91 | 2952420 | 32444 | 84.0% | 38619 | 92.4% | 41794 | 4.5% | 43783 | 43869 | 43348 | 44396 | 44000 (43500-44500) |
2010/III
| 92 | 3060450 | 33266 | 84.1% | 39564 | 92.4% | 42800 | 4.2% | 44681 | 44618 | 44096 | 45146 | 44500 (44000-45000) |
2010/IV
| 92 | 3208470 | 34875 | 84.0% | 41494 | 92.3% | 44947 | 3.9% | 46790 | 45367 | 44847 | 45892 | 45500 (45000-46000) |
2011/I
| 90 | 3021690 | 33574 | 83.3% | 40316 | 92.3% | 43696 | 3.7% | 45388 | 46115 | 45599 | 46636 | 46000 (45500-46500) |
2011/II
| 91 | 3162900 | 34757 | 83.2% | 41771 | 92.3% | 45256 | 3.5% | 46888 | 46862 | 46349 | 47379 | 47000 (46500-47500) |
2011/III
| 92 | 3301830 | 35889 | 83.2% | 43160 | 92.4% | 46721 | 3.3% | 48301 | 47607 | 47095 | 48124 | 47500 (47000-48000) |
2011/IV
| 92 | 3414960 | 37119 | 83.2% | 44619 | 92.5% | 48217 | 3.1% | 49756 | 48351 | 47832 | 48874 | 48500 (48000-49000) |
2012/I
| 91 | 3268320 | 35916 | 83.9% | 42827 | 92.6% | 46271 | 2.9% | 47652 | 49092 | 48555 | 49634 | 49000 (48500-49500) |
2012/II
| 91 | 3356700 | 36887 | 83.8% | 44007 | 92.6% | 47543 | 2.9% | 48944 | 49831 | 49260 | 50407 | 50000 (49500-50500) |
2012/III
| 92 | 3447960 | 37478 | 83.6% | 44816 | 92.4% | 48483 | 2.7% | 49819 | 50566 | 49942 | 51197 | 50500 (50000-51000) |
2012/IV
| 92 | 3632040 | 39479 | 83.6% | 47240 | 92.5% | 51089 | 2.4% | 52344 | 51298 | 50599 | 52006 | 51500 (50500-52000) |
2013/I
| 90 | 3467760 | 38531 | 84.0% | 45861 | 92.7% | 49478 | 2.2% | 50591 | 52026 | 51230 | 52834 | 52000 (51000-53000) |
2013/II
| 91 | 3657690 | 40194 | 84.0% | 47861 | 92.8% | 51555 | 2.0% | 52585 | 52748 | 51834 | 53677 | 52500 (52000-53500) |
2103/III
| 92 | 3768660 | 40964 | 84.0% | 48791 | 92.7% | 52657 | 1.8% | 53639 | 53466 | 52413 | 54539 | 53500 (52500-54500) |
2013/IV
| 92 | 3838620 | 41724 | 83.9% | 49719 | 92.5% | 53776 | 2.0% | 54849 | 54178 | 52967 | 55416 | 54000 (53000-55500) |