Background
Patients and methods
Patients
Measurements
Study design
Statistical analysis
Results
Characteristics | |
Female, n (%) | 24 (32) |
Age, years | 58 (48–68) |
SOFA | 5 (4–7) |
Duration of mechanical ventilation, days | 4 (2–6) |
Main reason for mechanical ventilation, n (%) | |
Acute respiratory failure | 28 (37) |
Shock | 24 (32) |
Coma | 23 (31) |
Ventilator parameters | |
Pressure support level, cmH2O | 10 (8–10) |
Tidal volume, ml/kg ideal body weight | 7 (5–8) |
PEEP, cmH2O | 5 (5–6) |
Clinical parameters | |
Breaths, min−1 | 22 (20–25) |
Mean arterial pressure, mmHg | 80 (69–98) |
Heart rate, min−1 | 89 (78–100) |
Arterial blood gases | |
pH | 7.44 (7.40–7.45) |
PaCO2, mmHg | 38 (34–44) |
PaO2/FiO2 | 279 (214–357) |
Prediction of spontaneous breathing trial failure
Threshold | AUC-ROC (95% CI) | Sensitivity (%) (95% CI) | Specificity (%) (95% CI) | Likelihood ratios (95% CI) | Predictive values (%) (95% CI) | |||
---|---|---|---|---|---|---|---|---|
Positive | Negative | Positive | Negative | |||||
Ptr,stim | 7.2 cmH2O | 0.80 (0.70–0.89) | 68 (47–84) | 79 (64–89) | 3.2 (1.7–5.8) | 0.4 (0.2–0.7) | 66 (51–78) | 80 (70–88) |
TFdi | 25.8% | 0.82 (0.73–0.93) | 79 (59–92) | 73 (58–85) | 2.9 (1.8–4.8) | 0.3 (0.1–0.6) | 63 (51–74) | 85 (74–92) |