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Effects of Lithium Salts on Memory

Published online by Cambridge University Press:  29 January 2018

K. S. Kusumo
Affiliation:
Department of Clinical Psychology, University of Indonesia, Jl Salemba No. 4, Jakarta, Indonesia
M. Vaughan
Affiliation:
Department of Psychiatry, University Hospital of South Manchester, West Didsbury, Manchester M20 SLR

Abstract

Thirteen patients diagnosed as having affective disorders, and who were taking lithium, were compared with drug-free controls on short-term and long-term memory tasks. There was some indication that patients on lithium may show an impairment of short-term memory at fifteen-second delay intervals, and possibly enhanced long-term recall of difficult material. Further comparison with results obtained from six patients on tricyclic antidepressants seemed to reduce the possibility that the lithium group's scores were a function of their psychiatric status.

As the group sizes were small, all the findings need to be replicated.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1977 

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References

Benowitz, L. & Sperry, R. W. (1973) Amnesic effects of lithium chloride in chicks. Experimental Neurology, 40, 540–6.Google Scholar
Johnson, F. N. (1976) The effect of lithium chloride on one trial passive avoidance learning in rats. British Journal of Pharmacology, 56, 8791.CrossRefGoogle ScholarPubMed
Johnson, F. N. & Baker, G. J. (1972) Effects of lithium chloride on learned responses. Diseases of the Nervous System, 33, 664–6.Google Scholar
Mark, R. F. & Watts, M. E. (1971) Drug inhibition of memory formation in chickens. I. Long term memory. Proceedings of the Royal Society of Medicine, 178, 439–54.Google Scholar
Peterson, L. R. & Peterson, M. J. (1959) Short term retention of individual verbal items. Journal of Experimental Psychology, 58, 193–8.Google Scholar
Shou, M. (1968) Lithium in psychiatric therapy and prophylaxis. Journal of Psychiatric Research, 6, 6795.Google Scholar
Stevens, S. S. (Ed.) (1966) Handbook of Experimental Psychology, p 54. John Wiley & Sons, Inc. Google Scholar
Watts, M. E. & Mark, R. F. (1971) Drug inhibition of memory function in chickens. II. Short term memory. Proceedings of the Royal Society of Medicine, 178, 445–64.Google ScholarPubMed
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