Erschienen in:
01.10.2012 | Melanomas
Can We Better Identify Thin Cutaneous Melanomas That are Likely to Metastasize and Cause Death?
verfasst von:
Rajmohan Murali, MD, Richard A. Scolyer, MD, John F. Thompson, MD
Erschienen in:
Annals of Surgical Oncology
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Ausgabe 11/2012
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Excerpt
Most patients with thin primary cutaneous melanomas (Breslow thickness ≤ 1 mm) have an excellent outcome, and only a minority experience tumor recurrence and death due to melanoma.
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3 For example, in the American Joint Committee on Cancer database, which contains information on a large number of patients treated at many international centers, the 10-year melanoma-specific survival for patients presenting with T1 melanomas (i.e., ≤ 1.0 mm in thickness) was 92 %.
4 In the United States, Europe, and Australia, the majority of patients with newly diagnosed cutaneous melanomas have thin tumors.
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8 Therefore, even though fewer than 10 % of patients with thin melanomas will eventually progress, this population constitutes a large number of individuals. It is clearly important to identify these higher-risk patients early in the course of their disease if possible, so that management plans appropriate for the biologic aggression of their tumors can be initiated. …
