Skip to main content
Erschienen in: Annals of Surgical Oncology 3/2016

01.03.2016 | Gynecologic Oncology

Is It Time to Centralize Ovarian Cancer Care in the United States?

verfasst von: Renee A. Cowan, MD, Roisin E. O’Cearbhaill, MD, Ginger J. Gardner, MD, Douglas A. Levine, MD, Kara Long Roche, MD, Yukio Sonoda, MD, Oliver Zivanovic, MD, William P. Tew, MD, Evis Sala, MD, PhD, Yulia Lakhman, MD, Hebert A. Vargas Alvarez, MD, Debra M. Sarasohn, MD, Svetlana Mironov, MD, Nadeem R. Abu-Rustum, MD, Dennis S. Chi, MD

Erschienen in: Annals of Surgical Oncology | Ausgabe 3/2016

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The purpose of this article was to broadly review the most up-to-date information pertaining to the centralization of ovarian cancer care in the United States (US) and worldwide.

Methods

Much of the present literature pertaining to disparities in, and centralization of, ovarian cancer care in the US and internationally was reviewed, and specifically included original research and review articles.

Results

Data show improved optimal debulking rates, National Comprehensive Cancer Network (NCCN) guideline adherence, and overall survival rates in higher-volume, more specialized hospitals, and amongst higher-volume providers.

Conclusions

Patients with invasive epithelial ovarian cancer, especially those with higher stages (III and IV), are better served by centralized care in high-volume hospitals and by high-volume physicians, who adhere to NCCN guidelines wherever possible. More research is needed to determine the policy changes that can increase NCCN guideline adherence in low-volume hospitals and low-provider caseload scenarios. Policy and future research should be aimed at increasing patient access, either directly or indirectly, to high-volume hospital and high-volume providers, especially amongst Medicare, lower socioeconomic status, and minority patients.
Literatur
1.
Zurück zum Zitat Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA Cancer Clin. 2015;65:5–29.CrossRef Siegel RL, Miller KD, Jemal A. Cancer statistics, 2015. CA Cancer Clin. 2015;65:5–29.CrossRef
2.
Zurück zum Zitat Bristow RE, Palis BE, Chi DS, Cliby WA. The National Cancer Database report on advanced-stage epithelial ovarian cancer: impact of hospital surgical case volume on overall survival and surgical treatment paradigm. Gynecol Oncol. 2010;118:262–7.CrossRefPubMed Bristow RE, Palis BE, Chi DS, Cliby WA. The National Cancer Database report on advanced-stage epithelial ovarian cancer: impact of hospital surgical case volume on overall survival and surgical treatment paradigm. Gynecol Oncol. 2010;118:262–7.CrossRefPubMed
3.
Zurück zum Zitat Hoskins W, Rice L, Rubin S. Ovarian cancer surgical practice guidelines. Society of Surgical Oncology practice guidelines. Oncology (Williston Park). 1997;11:896–900.PubMed Hoskins W, Rice L, Rubin S. Ovarian cancer surgical practice guidelines. Society of Surgical Oncology practice guidelines. Oncology (Williston Park). 1997;11:896–900.PubMed
4.
Zurück zum Zitat Reade C, Elit L. Trends in gynecologic cancer care in North America. Obstet Gynecol Clin N Am. 2012;39:107–29.CrossRef Reade C, Elit L. Trends in gynecologic cancer care in North America. Obstet Gynecol Clin N Am. 2012;39:107–29.CrossRef
5.
Zurück zum Zitat Vernooij F, Heintz AP, Coebergh JW, Massuger LF, Witteveen PO, van der Graaf Y. Specialized and high-volume care leads to better outcomes of ovarian cancer treatment in the Netherlands. Gynecol Oncol. 2009;112:455–61.CrossRefPubMed Vernooij F, Heintz AP, Coebergh JW, Massuger LF, Witteveen PO, van der Graaf Y. Specialized and high-volume care leads to better outcomes of ovarian cancer treatment in the Netherlands. Gynecol Oncol. 2009;112:455–61.CrossRefPubMed
7.
Zurück zum Zitat Shalowitz DI, Vinograd AM, Giuntoli RL 2nd. Geographic access to gynecologic cancer care in the United States. Gynecol Oncol. 2015;138:115–20.CrossRefPubMed Shalowitz DI, Vinograd AM, Giuntoli RL 2nd. Geographic access to gynecologic cancer care in the United States. Gynecol Oncol. 2015;138:115–20.CrossRefPubMed
8.
Zurück zum Zitat Wright JD, Herzog TJ, Siddiq Z, et al. Failure to rescue as a source of variation in hospital mortality for ovarian cancer. J Clin Oncol. 2012;30:3976–82.CrossRefPubMed Wright JD, Herzog TJ, Siddiq Z, et al. Failure to rescue as a source of variation in hospital mortality for ovarian cancer. J Clin Oncol. 2012;30:3976–82.CrossRefPubMed
9.
Zurück zum Zitat Long B, Chang J, Ziogas A, Tewari KS, Anton-Culver H, Bristow RE. Impact of race, socioeconomic status, and the health care system on the treatment of advanced-stage ovarian cancer in California. Am J Obstet Gynecol. 2015;212:468.e1–9. Long B, Chang J, Ziogas A, Tewari KS, Anton-Culver H, Bristow RE. Impact of race, socioeconomic status, and the health care system on the treatment of advanced-stage ovarian cancer in California. Am J Obstet Gynecol. 2015;212:468.e1–9.
10.
Zurück zum Zitat Cliby WA, Powell MA, Al-Hammadi N, et al. Ovarian cancer in the United States: contemporary patterns of care associated with improved survival. Gynecol Oncol. 2015;136:11–7.CrossRefPubMed Cliby WA, Powell MA, Al-Hammadi N, et al. Ovarian cancer in the United States: contemporary patterns of care associated with improved survival. Gynecol Oncol. 2015;136:11–7.CrossRefPubMed
11.
Zurück zum Zitat Bristow RE, Chang J, Ziogas A, Randall LM, Anton-Culver H. High-volume ovarian cancer care: survival impact and disparities in access for advanced-stage disease. Gynecol Oncol. 2014;132:403–10.CrossRefPubMed Bristow RE, Chang J, Ziogas A, Randall LM, Anton-Culver H. High-volume ovarian cancer care: survival impact and disparities in access for advanced-stage disease. Gynecol Oncol. 2014;132:403–10.CrossRefPubMed
12.
Zurück zum Zitat Mercado C, Zingmond D, Karlan BY, et al. Quality of care in advanced ovarian cancer: the importance of provider specialty. Gynecol Oncol. 2010;117:18–22.CrossRefPubMed Mercado C, Zingmond D, Karlan BY, et al. Quality of care in advanced ovarian cancer: the importance of provider specialty. Gynecol Oncol. 2010;117:18–22.CrossRefPubMed
13.
Zurück zum Zitat Bristow RE, Chang J, Ziogas A, Campos B, Chavez LR, Anton-Culver H. Impact of National Cancer Institute Comprehensive Cancer Centers on ovarian cancer treatment and survival. J Am Coll Surg. 2015;220:940–50.CrossRefPubMedPubMedCentral Bristow RE, Chang J, Ziogas A, Campos B, Chavez LR, Anton-Culver H. Impact of National Cancer Institute Comprehensive Cancer Centers on ovarian cancer treatment and survival. J Am Coll Surg. 2015;220:940–50.CrossRefPubMedPubMedCentral
14.
Zurück zum Zitat Ioka A, Tsukuma H, Ajiki W, Oshima A. Influence of hospital procedure volume on ovarian cancer survival in Japan, a country with low incidence of ovarian cancer. Cancer Sci. 2004;95:233–7.CrossRefPubMed Ioka A, Tsukuma H, Ajiki W, Oshima A. Influence of hospital procedure volume on ovarian cancer survival in Japan, a country with low incidence of ovarian cancer. Cancer Sci. 2004;95:233–7.CrossRefPubMed
15.
Zurück zum Zitat Doufekas K, Olaitan A. Clinical epidemiology of epithelial ovarian cancer in the UK. Int J Womens Health. 2014;6:537–45.PubMedPubMedCentral Doufekas K, Olaitan A. Clinical epidemiology of epithelial ovarian cancer in the UK. Int J Womens Health. 2014;6:537–45.PubMedPubMedCentral
16.
Zurück zum Zitat Woo YL, Kyrgiou M, Bryant A, Everett T, Dickinson HO. Centralisation of services for gynaecological cancers: a Cochrane systematic review. Gynecol Oncol. 2012;126:286–90.CrossRefPubMed Woo YL, Kyrgiou M, Bryant A, Everett T, Dickinson HO. Centralisation of services for gynaecological cancers: a Cochrane systematic review. Gynecol Oncol. 2012;126:286–90.CrossRefPubMed
17.
Zurück zum Zitat Kumpulainen S, Kuoppala T, Leminen A, et al. Surgical treatment of ovarian cancer in different hospital categories: a prospective nation-wide study in Finland. Eur J Cancer. 2006;42:388–95.CrossRefPubMed Kumpulainen S, Kuoppala T, Leminen A, et al. Surgical treatment of ovarian cancer in different hospital categories: a prospective nation-wide study in Finland. Eur J Cancer. 2006;42:388–95.CrossRefPubMed
18.
Zurück zum Zitat Paulsen T, Kjaerheim K, Kaern J, Tretli S, Tropé C. Improved short-term survival for advanced ovarian, tubal, and peritoneal cancer patients operated at teaching hospitals. Int J Gynecol Cancer. 2006;16 Suppl. 1:11–7.CrossRefPubMed Paulsen T, Kjaerheim K, Kaern J, Tretli S, Tropé C. Improved short-term survival for advanced ovarian, tubal, and peritoneal cancer patients operated at teaching hospitals. Int J Gynecol Cancer. 2006;16 Suppl. 1:11–7.CrossRefPubMed
19.
Zurück zum Zitat Bristow RE, Chang J, Ziogas A, Anton-Culver H, Vieira VM. Spatial analysis of adherence to treatment guidelines for advanced-stage ovarian cancer and the impact of race and socioeconomic status. Gynecol Oncol. 2014;134:60–7.CrossRefPubMedPubMedCentral Bristow RE, Chang J, Ziogas A, Anton-Culver H, Vieira VM. Spatial analysis of adherence to treatment guidelines for advanced-stage ovarian cancer and the impact of race and socioeconomic status. Gynecol Oncol. 2014;134:60–7.CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Von Meyenfeldt EM, Gooiker GA, van Gijn W, et al. The relationship between volume or surgeon specialty and outcome in the surgical treatment of lung cancer: a systematic review and meta-analysis. J Thorac Oncol. 2012;7:1170–8.CrossRef Von Meyenfeldt EM, Gooiker GA, van Gijn W, et al. The relationship between volume or surgeon specialty and outcome in the surgical treatment of lung cancer: a systematic review and meta-analysis. J Thorac Oncol. 2012;7:1170–8.CrossRef
21.
Zurück zum Zitat Wouters MW, Karim-Kos HE, le Cessie S, et al. Centralization of esophageal cancer surgery: does it improve clinical outcome? Ann Surg Oncol. 2009;16:1789–98.CrossRefPubMedPubMedCentral Wouters MW, Karim-Kos HE, le Cessie S, et al. Centralization of esophageal cancer surgery: does it improve clinical outcome? Ann Surg Oncol. 2009;16:1789–98.CrossRefPubMedPubMedCentral
22.
Zurück zum Zitat Singla A, Broadbridge V, Mittinty M, Beeke C, Maddern GJ. Rural populations have equal surgical and survival outcomes in metastatic colorectal cancer. Aust J Rural Health. 2014; 22:249–56.CrossRefPubMed Singla A, Broadbridge V, Mittinty M, Beeke C, Maddern GJ. Rural populations have equal surgical and survival outcomes in metastatic colorectal cancer. Aust J Rural Health. 2014; 22:249–56.CrossRefPubMed
23.
Zurück zum Zitat Lemmens VE, Bosscha K, van der Schelling G, Brenninkmeijer S, Coebergh JW, de Hingh IH. Improving outcome for patients with pancreatic cancer through centralization. Br J Surg. 2011;98:1455–62.CrossRefPubMed Lemmens VE, Bosscha K, van der Schelling G, Brenninkmeijer S, Coebergh JW, de Hingh IH. Improving outcome for patients with pancreatic cancer through centralization. Br J Surg. 2011;98:1455–62.CrossRefPubMed
24.
Zurück zum Zitat Joudi FN, Konety BR. The impact of provider volume on outcomes from urological cancer therapy. J Urol. 2005;174:432–8.CrossRefPubMed Joudi FN, Konety BR. The impact of provider volume on outcomes from urological cancer therapy. J Urol. 2005;174:432–8.CrossRefPubMed
25.
Zurück zum Zitat Zivanovic O, Aldini A, Carlson JW, Chi DS. Advanced cytoreductive surgery: American perspective. Gynecol Oncol. 2009;114 (2 Suppl.):S3–S9.CrossRefPubMed Zivanovic O, Aldini A, Carlson JW, Chi DS. Advanced cytoreductive surgery: American perspective. Gynecol Oncol. 2009;114 (2 Suppl.):S3–S9.CrossRefPubMed
26.
Zurück zum Zitat Morgan RJ Jr, Alvarez RD, Armstrong DK, et al. Epithelial ovarian cancer. J Natl Compr Cancer Netw. 2011;9:82–113.CrossRef Morgan RJ Jr, Alvarez RD, Armstrong DK, et al. Epithelial ovarian cancer. J Natl Compr Cancer Netw. 2011;9:82–113.CrossRef
27.
Zurück zum Zitat Phippen NT, Barnett JC, Lowery WJ, Miller CR, Leath CA 3rd. Surgical outcomes and national comprehensive cancer network compliance in advanced ovarian cancer surgery in a low volume military treatment facility. Gynecol Oncol. 2013;131:158–62.CrossRefPubMed Phippen NT, Barnett JC, Lowery WJ, Miller CR, Leath CA 3rd. Surgical outcomes and national comprehensive cancer network compliance in advanced ovarian cancer surgery in a low volume military treatment facility. Gynecol Oncol. 2013;131:158–62.CrossRefPubMed
28.
Zurück zum Zitat Bristow RE, Chang J, Ziogas A, Anton-Culver H. Adherence to treatment guidelines for ovarian cancer as a measure of quality care. Obstet Gynecol. 2013;121:1226–34.CrossRefPubMed Bristow RE, Chang J, Ziogas A, Anton-Culver H. Adherence to treatment guidelines for ovarian cancer as a measure of quality care. Obstet Gynecol. 2013;121:1226–34.CrossRefPubMed
29.
Zurück zum Zitat Bristow RE, Santillan A, Diaz-Montes TP, et al. Centralization of care for patients with advanced-stage ovarian cancer: a cost-effectiveness analysis. Cancer. 2007;109:1513–22.CrossRefPubMed Bristow RE, Santillan A, Diaz-Montes TP, et al. Centralization of care for patients with advanced-stage ovarian cancer: a cost-effectiveness analysis. Cancer. 2007;109:1513–22.CrossRefPubMed
30.
Zurück zum Zitat Greving JP, Vernooij F, Heintz AP, van der Graaf Y, Buskens E. Is centralization of ovarian cancer care warranted? A cost-effectiveness analysis. Gynecol Oncol. 2009;113:68–74.CrossRefPubMed Greving JP, Vernooij F, Heintz AP, van der Graaf Y, Buskens E. Is centralization of ovarian cancer care warranted? A cost-effectiveness analysis. Gynecol Oncol. 2009;113:68–74.CrossRefPubMed
31.
Zurück zum Zitat Aune G, Torp SH, Syversen U, Hagen B, Tingulstad S. Ten years’ experience with centralized surgery of ovarian cancer in one health region in Norway. Int J Gynecol Cancer. 2012;22:226–31.CrossRefPubMed Aune G, Torp SH, Syversen U, Hagen B, Tingulstad S. Ten years’ experience with centralized surgery of ovarian cancer in one health region in Norway. Int J Gynecol Cancer. 2012;22:226–31.CrossRefPubMed
32.
Zurück zum Zitat Wright AA, Cronin A, Milne DE, et al. Use and effectiveness of intraperitoneal chemotherapy for treatment of ovarian cancer. J Clin Oncol. 2015;33:2841–7.CrossRefPubMedPubMedCentral Wright AA, Cronin A, Milne DE, et al. Use and effectiveness of intraperitoneal chemotherapy for treatment of ovarian cancer. J Clin Oncol. 2015;33:2841–7.CrossRefPubMedPubMedCentral
Metadaten
Titel
Is It Time to Centralize Ovarian Cancer Care in the United States?
verfasst von
Renee A. Cowan, MD
Roisin E. O’Cearbhaill, MD
Ginger J. Gardner, MD
Douglas A. Levine, MD
Kara Long Roche, MD
Yukio Sonoda, MD
Oliver Zivanovic, MD
William P. Tew, MD
Evis Sala, MD, PhD
Yulia Lakhman, MD
Hebert A. Vargas Alvarez, MD
Debra M. Sarasohn, MD
Svetlana Mironov, MD
Nadeem R. Abu-Rustum, MD
Dennis S. Chi, MD
Publikationsdatum
01.03.2016
Verlag
Springer International Publishing
Erschienen in
Annals of Surgical Oncology / Ausgabe 3/2016
Print ISSN: 1068-9265
Elektronische ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-015-4938-9

Weitere Artikel der Ausgabe 3/2016

Annals of Surgical Oncology 3/2016 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

CME: 2 Punkte

Prof. Dr. med. Gregor Antoniadis Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

CME: 2 Punkte

Dr. med. Benjamin Meyknecht, PD Dr. med. Oliver Pieske Das Webinar S2e-Leitlinie „Distale Radiusfraktur“ beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

CME: 2 Punkte

Dr. med. Mihailo Andric
Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.