Extraction and Purification of Effective Antimicrobial Constituents of Terminalia chebula RETS. against Methicillin-Resistant Staphylococcus aureus

Youichi SATO; Hideki OKETANI; Kenichi SINGYOUCHI; Tetsuya OHTSUBO; Masaru KIHARA; Hirofumi SHIBATA; Tomihiko HIGUTI

doi:10.1248/bpb.20.401

Youichi SATO, Hideki OKETANI, Kenichi SINGYOUCHI, Tetsuya OHTSUBO, Masaru KIHARA, Hirofumi SHIBATA, Tomihiko HIGUTI

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Keywords: Terminalia chebula, antimicrobial activity, MRSA, gallic acid, ethyl gallate

JOURNAL FREE ACCESS

1997 Volume 20 Issue 4 Pages 401-404

DOI https://doi.org/10.1248/bpb.20.401

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Abstract

Examination of the EtOH extract of the fruiting bodies of Terminalia chebula RETZ. led to the isolation of two potent antimicrobial substances against even methicillin-resistant strains of Staphylococcus aureus. On the basis of spectroscopic evidence, the two isolates have been identified as gallic acid and its ethyl ester.

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