Inhibitory Activity of Lignan Components from the Flower Buds of Magnoliae fargesii on the Expression of Cell Adhesion Molecules

Kyung-Seop AHN; Keun Young JUNG; Jung-Hee KIM; Sei Ryang OH; Hyeong-Kyu LEE

doi:10.1248/bpb.24.1085

Notes

Inhibitory Activity of Lignan Components from the Flower Buds of Magnoliae fargesii on the Expression of Cell Adhesion Molecules

Kyung-Seop AHN, Keun Young JUNG, Jung-Hee KIM, Sei Ryang OH, Hyeong-Kyu LEE

Author information

Keywords: intercellular adhesion molecule-1, vascular cell adhesion molecule-1, Magnoliae fargesii, lignan

JOURNAL FREE ACCESS

2001 Volume 24 Issue 9 Pages 1085-1087

DOI https://doi.org/10.1248/bpb.24.1085

Details

Abstract

Inhibitory activity of lignans isolated from Magnoliae fargesii CHENG on cell adhesion molecules on the surface of THP-1 human monocytic cell lines were investigated. Among 16 lignan components tested, six displayed relatively potent inhibitory activity on the expression of both intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1).

Corresponding author

Register with J-STAGE for free!