Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Comparative Studies on Angiotensins. IV. Structure of Snake (Elaphe climocophora) Angiotensin
TAEKO NAKAYAMATERUMI NAKAJIMAHIROFUMI SOKABE
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1977 Volume 25 Issue 12 Pages 3255-3260

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Abstract

Three kinds of snake angiotensins have been isolated from the incubation product of snake (Elaphe climocophora) kidney extract with homologous plasma. The amino acid sequences were deduced by dansyl method as follows : Asp-Arg-Val-Tyr-Val-His-Pro-Phe X-Asx-Arg-Val-Tyr-Val-His-Pro-Phe-Tyr X-Asx-Arg-Val-Tyr-Val-His-Pro-Phe-Tyr-Leu Tyrosine in position 9 was different from histidine of mammalian angiotensins or serine of the fowl. Position 5 was valine as in so-called bovine angiotensin.

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© The Pharmaceutical Society of Japan
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