Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Cholestane Glycosides from the Bulbs of Galtonia candicans and Their Cytotoxicity
Minpei KURODAYoshihiro MIMAKIAkihito YOKOSUKAYutaka SASHIDA
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JOURNAL FREE ACCESS

2001 Volume 49 Issue 8 Pages 1042-1046

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Abstract

Further search for cytotoxic compounds contained in the bulbs of Galtonia candicans (Liliaceae) led to the isolation of four potent cytotoxic cholestane glycosides (1-4) based upon 3β, 16β, 17α-trihydroxycholest-5-en-22-one, three of which (2-4) have not been reported previously. A new cholestane bisdesmoside (5) and a new rearranged cholestane glycoside (6) were also isolated. The structural assignment of the new constituents was carried out by spectroscopic analysis and a few chemical transformations.

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© 2001 The Pharmaceutical Society of Japan
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