Two Triterpene Saponins from Achyranthes bidentata

Anne-Claire MITAINE-OFFER; Abderrazak MAROUF; Bernard HANQUET; Nicolas BIRLIRAKIS; Marie-Aleth LACAILLE-DUBOIS

doi:10.1248/cpb.49.1492

Notes

Two Triterpene Saponins from Achyranthes bidentata

Anne-Claire MITAINE-OFFER, Abderrazak MAROUF, Bernard HANQUET, Nicolas BIRLIRAKIS, Marie-Aleth LACAILLE-DUBOIS

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Keywords: Achyranthes bidentata, Amaranthaceae, triterpene-saponin

JOURNAL FREE ACCESS

2001 Volume 49 Issue 11 Pages 1492-1494

DOI https://doi.org/10.1248/cpb.49.1492

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Abstract

Bidentatoside II (1) and chikusetsusaponin V methyl ester (2) are two further triterpene saponins isolated from the roots of Achyranthes bidentata. Chemical and homo and heteronuclear two-dimensional (2D) NMR techniques have led to the structural elucidation of 1 which is a new seco-glycoside of oleanolic acid and the full ¹H- and ¹³C-NMR assignments of 2. These compounds did not show any potentiation of the in vitro cytotoxicity of cisplatin in the HT 29 human colon cancer cell line.

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