Two New Lactones and One New Aryl-8-oxa-bicyclo[3,2,1]oct-3-en-2-one from Descurainia sophia

Kai Sun; Xian Li; Wen Li; Jinhui Wang; Jianming Liu; Yi Sha

doi:10.1248/cpb.52.1483

Notes

Two New Lactones and One New Aryl-8-oxa-bicyclo[3,2,1]oct-3-en-2-one from Descurainia sophia

Kai Sun, Xian Li, Wen Li, Jinhui Wang, Jianming Liu, Yi Sha

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Keywords: Descurainia sophia, lactone, aryl-8-oxa-bicyclo[3,2,1]-oct-3-en-2-one, nor-lignan, cytotoxicity

JOURNAL FREE ACCESS

2004 Volume 52 Issue 12 Pages 1483-1486

DOI https://doi.org/10.1248/cpb.52.1483

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Abstract

Two new lactones (1, 2), descurainolide A and B, and one new aryl-8-oxa-bicyclo[3,2,1]-oct-3-en-2-one (3), descurainin, together with five known compounds (4—8), were isolated from the seeds of Descurainia sophia (L.) WEBB ex PRANTL. The structures of the new compounds were elucidated by extensive studies of their 1D, 2D NMR and HR-MS. Compounds 4 and 5 showed cytotoxicity.

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