Circulation Journal
Online ISSN : 1347-4820
Print ISSN : 1346-9843
ISSN-L : 1346-9843
Reviews
Myocardial T1 Mapping
– Hope or Hype? –
Heerajnarain BulluckViviana MaestriniStefania RosminiAmna Abdel-GadirThomas A TreibelSilvia CastellettiChiara Bucciarelli-DucciCharlotte ManistyJames C. Moon
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2015 Volume 79 Issue 3 Pages 487-494

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Abstract

Cardiovascular magnetic resonance is a well-established tool for the quantification of focal fibrosis. With the introduction of T1 mapping, diffuse myocardial processes can be detected and quantified. In particular, infiltration and storage disorders with large disease-related changes, and diffuse fibrosis where measurement is harder but the potential impact larger. This has added a new dimension to the understanding and assessment of various myocardial diseases. T1 mapping promises to detect early disease, quantify disease severity and provide prognostic insights into certain conditions. It also has the potential to be a robust surrogate marker in drug development trials to monitor therapeutic response and be a prognostic marker in certain diseases. T1 mapping is an evolving field and numerous factors currently preclude its standardization. In this review, we describe the current status of T1 mapping and its potential promises and pitfalls. (Circ J 2015; 79: 487–494)

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© 2015 THE JAPANESE CIRCULATION SOCIETY
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