09 May 2019 : Review article
Current Status of Functional Studies on Circular RNAs in Bladder Cancer and their Potential Role as Diagnostic and Prognostic Biomarkers: A Review
Liang Cong1A, Qiwei Yang2C, Chunmei Hu3B, Qiong Yu3DF, Shuhong Hao3EF*, Dongfu Li1GDOI: 10.12659/MSM.916697
Med Sci Monit 2019; 25:3425-3434
Abstract
Worldwide, bladder cancer represents the ninth most common malignancy and is the 13th cause of cancer-associated death. Although surgery combined with chemotherapy and radiotherapy has improved patient outcomes, the prognosis remains poor for most patients with muscle-invasive bladder cancer. The exact mechanisms and critical regulators of bladder cancer remain unknown. Circular RNAs (circRNAs) are a distinct type of endogenous non-coding RNA. Recent studies have shown that circRNAs participate in many processes, including proliferation, invasion, migration, and apoptosis in multiple types of malignancy, including bladder cancer. Some circRNAs are dysregulated in bladder cancer and play essential roles in cancer progression. Importantly, some circRNAs may serve as diagnostic and prognostic biomarkers for bladder cancer. This review aims to summarize the findings from recent studies that have focused on the roles of human circRNAs in bladder cancer and discusses the clinical roles for circRNAs, including their potential roles as diagnostic or prognostic biomarkers.
Keywords: Biological Markers, Diagnosis, Carcinoma, Transitional Cell, RNA, Untranslated, Biomarkers, Tumor, RNA, RNA, Circular
Editorial
01 May 2024 : Editorial
Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) – Lifileucel (Amtagvi)DOI: 10.12659/MSM.944927
Med Sci Monit 2024; 30:e944927
In Press
Animal Research
Enhanced Bone Healing Through Systemic Capsaicin Administration: An Experimental Study on Wistar RatsMed Sci Monit In Press; DOI: 10.12659/MSM.942485
Clinical Research
Differential Inflammatory Responses in Adult and Pediatric COVID-19 Patients: Implications for Long-Term Co...Med Sci Monit In Press; DOI: 10.12659/MSM.944052
Clinical Research
Effectiveness of Shoulder Taping in Treating Hemiplegic Shoulder Subluxation: A Randomized Controlled Study...Med Sci Monit In Press; DOI: 10.12659/MSM.944222
Clinical Research
Comparison of Fentanyl, Ketamine, and Lidocaine Combined with Propofol Anesthesia in Patients with Crohn Di...Med Sci Monit In Press; DOI: 10.12659/MSM.944116
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952