Chest
ORIGINAL RESEARCHPULMONARY VASCULAR DISEASEReproducibility of Right Ventricular Volumes and Ejection Fraction Using Real-time Three-Dimensional Echocardiography: Comparison With Cardiac MRI
Section snippets
Study Design
We prospectively recruited patients who had been referred to the echocardiography laboratory for the assessment of cardiac structure and function after experiencing an acute myocardial infarction, and who were scheduled to undergo 2DE, RT3DE, and MRI. In 54 patients (47 men; mean [± SD] age, 63 ± 10 years), RV involvement was suspected from standard imaging, and an additional medial RV view was obtained using RT3DE (see “RT3DE” section below). The investigations were approved by the Human
Patient Characteristics
Of the 54 original patients, 2 were excluded from RT3DE as they were unable to hold their breath during acquisition, and another 2 were excluded from the MRI validation due to claustrophobia. Therefore, the results of the MRI, RT3DE, and 2DE were analyzed in 50 patients (43 men; mean age, 62 ± 11 years). All patients had LV regional wall motion abnormalities, with 70% of patients undergoing angiography. The majority had multivessel coronary artery disease (defined by > 70% stenosis in more than
Discussion
The results of this study of patients with ischemic LV dysfunction and suspicion of RV involvement indicate that RV volume measurements using RT3DE imaging are comparable with MRI. RT3DE also provides low test-retest variation and high reproducibility of RV measurements between observers.
Conclusions
In this study, RT3DE was the most accurate echocardiographic technique used for the measurement of RV volumes in subjects with LV dysfunction. It also appears to be a feasible follow-up imaging tool for sequential measurements of the RV volumes and function.
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Supported in part by a grant-in-aid from the National Health and Medical Research Council of Australia.
The authors have reported to the ACCP that no significant conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.