Chest
Original ResearchQuality of LifeThe Impact of Critical Illness on Perceived Health-Related Quality of Life During ICU Treatment, Hospital Stay, and After Hospital Discharge: A Long-term Follow-up Study
Section snippets
Materials and Methods
All patients admitted for > 48 h to a 10-bed closed-format mixed surgical-medical ICU of a 654-bed university-affiliated hospital in the Netherlands were eligible for the study. Between September 2000 and April 2004, all 2,127 patients admitted to the ICU were screened for study participation (Fig 1). In patients readmitted to the ICU (n = 36), data on HRQOL at discharge from the final ICU admission were included in the study. All patients surviving the 6-month follow-up period were included in
Results
Of the 2,127 patients screened, 1,676 patients were excluded (Fig 1). Of these excluded patients, 179 died while in the ICU (10.7%) and 87 died while on the general ward (5.2%). In the 451 patients included in the study, HRQOL was measured on ICU admission, and in 252 patients at the 6-month follow-up. At that time, 159 patients had died and 40 patients (9%) were lost to follow-up (Fig 1). The demographic and clinical characteristics of the patients lost to follow-up did not differ from the
Discussion
Both the change in HRQOL during ICU admission and its immediate recovery following ICU discharge have never been studied. This long-term prospective study evaluated the impact of critical illness on the perceived HRQOL in patients admitted to the ICU for > 48 h and surviving up to 6 months following ICU discharge. Before ICU admission, HRQOL was already impaired when compared to the healthy population. This was even more pronounced in the nonsurvivors. Critical illness caused a significant drop
References (37)
- et al.
Quality of life following critical care: moving beyond survival
Intensive Care Med
(2000) - et al.
Health-related quality of life before, 1 month after, and 9 months after intensive care in medical cardiovascular and pulmonary patients
Crit Care Med
(2003) - et al.
Long-term outcomes in survivors from critical illness
Anaesthesia
(2004) - et al.
Surviving intensive care: a report from the 2002 Brussels Roundtable
Intensive Care Med
(2003) - et al.
Reliability of the next of kins' estimates of critically ill patients' quality of life
Anaesthesia
(1997) - et al.
Frequency and methodologic rigor of quality-of-life assessments in the critical care literature
Crit Care Med
(1998) - et al.
Quality of life before and after intensive care
Anaesthesia
(2005) - et al.
Long-term outcome in ICU patients: what about quality of life?
Intensive Care Med
(2003) - et al.
Health-related quality of life of patients with multiple organ dysfunction: individual changes and comparison with normative population
Crit Care Med
(2003) - et al.
Changes in quality of life after medical intensive care
Intensive Care Med
(2001)
Two-year cognitive, emotional, and quality-of-life outcomes in acute respiratory distress syndrome
Am J Respir Crit Care Med
Understanding the treatment preferences of seriously ill patients
N Engl J Med
Informed consent in clinical trials in critical care: experience from the PAC-Man Study
Intensive Care Med
Quality of life on admission to the intensive care: can we query the relatives?
Intensive Care Med
Translation, validation, and norming of the Dutch language version of the SF-36 health survey in community and chronic disease populations
J Clin Epidemiol
Validating the SF-36 health survey questionnaire: new outcome measure for primary care
BMJ
Short form 36 in the intensive care unit: assessment of acceptability, reliability and validity of the questionnaire
Anaesthesia
Comparison of methods for the scoring and statistical analysis of SF-36 health profile and summary measures: summary of results from the Medical Outcomes Study
Med Care
Cited by (147)
Reduced quality of life in ICU survivors - the story behind the numbers: A mixed methods study
2021, Journal of Critical Care
This study was designed and started at the Gelre Hospital in Apeldoorn at the time that Dr. Bakker was still working there.
The authors have reported to the ACCP that no significant conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.