Chest
Original ResearchCritical Care MedicineLate Admission to the ICU in Patients With Community-Acquired Pneumonia Is Associated With Higher Mortality
Section snippets
Methods
This is a retrospective cohort study of patients hospitalized with CAP at two academic tertiary care hospitals in San Antonio, Texas. The Institutional Review Board of the University Health Science Center at San Antonio classified this project as an exempt study.
Results
We identified 161 patients who were admitted to the ICU with a diagnosis of severe CAP with confirmatory radiology that met our eligibility criteria. Out of these, 88% (n = 142) of patients had direct ICU admission or admission within 24 h of presentation (EICUA) and 19 patients had late ICU admission (LICUA).
Discussion
The main finding of our study was that patients with severe CAP admitted to the ICU after 24 h of hospital admission have a much higher mortality compared with those with direct admission within 24 h of presentation. In addition, the survival curves suggest that those patients with late admission to the ICU, whether in days 2 to 4 or 5 to 9 had similar rates of higher mortality when compared with patients admitted directly to the ICU or within 24 h, respectively. Despite the numerical longer
Acknowledgments
Author contributions: Dr Restrepo: contributed to design, data analysis, interpretation, and manuscript preparation.
Dr Mortensen: contributed to designing and securing funding for the primary study and participated in design, data analysis, interpretation, and manuscript revision.
Dr Rello: contributed to design, interpretation, and manuscript revision.
Dr Brody: contributed to design, interpretation, and manuscript revision.
Dr Anzueto: contributed to design, interpretation, and manuscript
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Funding/Support: Dr Restrepo is supported by a Department of Veteran Affairs Veterans Integrated Service Network 17 new faculty grant and National Health Institute grant KL2 RR025766. Dr Mortensen was supported by Howard Hughes Medical Institute faculty-start up grant 00378-001 and a Department of Veteran Affairs Veterans Integrated Service Network 17 new faculty grant.
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