Chest
Selected ReportsSpontaneous Pulmonary Hemorrhage Following Coronary Thrombolysis
Section snippets
CASE REPORT
A 52-year-old man presented to St. Vincent's Hospital with an acute anterior wall myocardial infarction. Chest pain had begun approximately one half hour prior to presentation. Physical examination on admission demonstrated blood pressure of 130/80 mm Hg, pulse rate of 84 beats per minute, and respiratory rate of 16 per minute. Chest examination revealed clear heart sounds, an atrial gallop, and no murmurs or rubs. Rales were heard at both lung bases. The ECG was significant for an acute
DISCUSSION
The majority of complications involved with thrombolytic therapy are primarily related to bleeding. The first TIMI trial reported bleeding, ecchymosis, or hematoma at the catheterization site in approximately two thirds of the patients. A major bleeding event defined as a reduction of hemoglobin of 5 g/dl or more or any intracranial bleed occurred in about 15 percent of patients studied.1 Our patient sustained a 40 percent reduction in hematocrit value during the 48 h period after
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Thrombolysis in myocardial infarction (TIMI) trial, Phase I: a comparison between intravenous tissue plasminogen activator and intravenous seroptokinase
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(1987) Pulmonary diseases and disorders
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Cited by (23)
Diffuse alveolar hemorrhage in immunocompetent patients: Etiologies and prognosis revisited
2012, Respiratory MedicineCitation Excerpt :Over 100 causes of DAH have been reported in immunocompetent patients (Table 1 of the online supplement).1,3,10,11 Most of the published series focus primarily on immune causes,2,5,8,12–14 but numerous non-immune causes of DAH have been reported as case reports.15–24 The relative frequency of the underlying causes of DAH, as well as their respective prognosis, is not well documented.
Iatrogenic drug effects in the Respiratory System
2002, Revista Portuguesa de PneumologiaDiffuse pulmonary hemorrhage after fibrinolytic therapy for acute myocardial infarction
1998, International Journal of Cardiology