Chest
Original ResearchCOPDPrognostic Value of the Objective Measurement of Daily Physical Activity in Patients With COPD
Section snippets
Subjects
We included 173 consecutive patients with COPD: postbronchodilator FEV1/FVC < 0.7 and postbronchodilator FEV1 < 80% predicted,1 cigarette smoking history of > 20 pack-years, stable condition for at least 2 months, and optimal medical therapy for at least 8 weeks. Exclusion criteria were history of asthma, depression, neuromuscular, or disabling cognitive problems; engagement in any exercise training program in the last 3 months; and other pathologic conditions or severe pain syndromes that
Results
One hundred fifty-seven men and 16 women with stable COPD were included in the study. Patient characteristics are given in Table 1.
Discussion
Our study provides an integrated evaluation of the impact of the objective measurement of daily physical activity on the prognosis of the COPD. Using a clinical cohort of patients with moderate to very severe COPD, treated according to current guidelines, we identify a linear dose-response relationship between levels of physical activity measured by an accelerometer and mortality or hospital admission. In addition to confirming that the reduction in daily physical activity is associated with a
Acknowledgments
Author contributions: Dr Garcia-Rio is the guarantor of the entire manuscript. The authors vouch for the veracity and completeness of the data and the data analyses.
Dr Garcia-Rio: contributed as the primary author, reviewing all data and writing the article.
Dr Rojo: contributed to developing the study protocol, interpreted data, contributed to and reviewed drafts of the manuscript, and approved the final version of the manuscript.
Dr Casitas: contributed to developing the study protocol, was a
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Funding/Support: This work was supported by the Sociedad Española de Neumología y Cirugía Torácica (SEPAR) and Sociedad Madrileña de Neumología y Cirugía Torácica (NEUMOMADRID) grants.
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