Chest
Selected ReportsRadiation Therapy for Tracheobronchial Amyloidosis
Section snippets
Case Report
In November 1994, a 67-year-old white male retired general contractor was admitted to the hospital for removal of an acoustic neuroma. His medical history was not significant and he was taking no medications. Findings from physical examination were unremarkable and results of laboratory tests, including serum chemistries, CBC count, and urinalysis, were normal. A preoperative chest radiograph showed partial collapse of the right middle lobe (RML). Bronchoscopy revealed abnormal mucosa in the
Discussion
Amyloidosis of the lower respiratory tract is a relatively rare disorder. Several literature reviews and small series6, 7, 8, 9, 10 have found that the tracheobronchial form of pulmonary amyloidosis accounts for 25 to 50% of the cases of amyloidosis limited to the lung. This patient had no clinical evidence of systemic amyloidosis, serum protein electrophoresis was normal, and tracheobronchial amyloidosis is generally thought not to be associated with systemic amyloidosis.6, 7, 8, 9 Therefore,
ACKNOWLEDGMENTS
We thank members of the Laser Surgery Institute (University of Utah Medical Center) and the Department of Anesthesiology for assistance in management of this challenging patient.
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Cited by (67)
External Beam Radiation Therapy: A Treatment Modality in Diffuse Tracheobronchial Amyloidosis
2015, Archivos de BronconeumologiaMultifocal primary amyloidosis of the airways: Case report and review of the literature
2015, Respiratory Medicine Case ReportsCitation Excerpt :EBRT is now recommended as a first -line therapy in patients with bulky or distal disease that is not amenable for bronchoscopic recanalization, especially if there is evidence of severe symptoms or functional decline. The successful use of radiation therapy for the treatment of TBA was first described by Kurrus et al. as a case report in 1998 [24]. A patient with life-threatening airway obstruction secondary to TBA received 20 Gy in 10 fractions to the distal and right main bronchi and 6 months later to the lower lobe bronchi.
Non-malignant central airway obstruction
2014, Archivos de Bronconeumologia
This work was supported by the Department of Veterans Affairs (VA), the Nora Eccles Treadwell Foundation, and the Richard A. and Nora Eccles Harrison Fund for Cardiovascular Research.