Chest
Clinical InvestigationsMUSCLESNonspecific Interstitial Pneumonia Associated With Polymyositis and Dermatomyositis: Serial High-Resolution CT Findings and Functional Correlation
Section snippets
Patient Selection
Between April 1996 and July 2001, 22 patients with either PM or DM underwent video-assisted thoracoscopic surgery for their pulmonary disease in our two university hospitals. The lung tissue was initially examined by a pathologist at each of our hospitals, and the findings were confirmed by consultation with an experienced pulmonary pathologist. Of the 22 patients, the histologic diagnosis included NSIP in 18 patients, UIP in 2 patients, BOOP with DAD in 1 patient, and unclassifiable diffuse
Results
The frequency and distribution of each abnormal opacity on the initial and follow-up high-resolution CT scans are indicated in Table 1. On the initial high-resolution CT scans, ground-glass opacity was the most frequent abnormality (13 patients) [Fig 1, top], followed by the presence of intralobular reticular opacity (12 patients) and traction bronchiectasis (12 patients) [Fig 2, top]. Septal line thickening was seen in 11 patients. When septal line thickening and intralobular reticular opacity
Discussion
High-resolution CT features of NSIP have been reported previously as patchy ground-glass opacity with or without consolidation.1617 However, in a study13 of 50 patients with idiopathic NSIP, a wide variety of high-resolution CT scan findings was reported including ground-glass opacity (76% of the cases), reticular opacity (46% of the cases), honeycomb lung (30% of the cases), consolidation (16% of the cases), and nodules (14% of the cases). In our patients with NSIP and PM/DM, the most common
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