Chest
Clinical InvestigationsSleep and BreathingObstructive Sleep Apnea Syndrome, Sleepiness, and Quality of Life
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Subjects
During a 12-month period, male subjects between 20 and 65 years of age, who had been referred for snoring, fatigue, and/or daytime sleepiness, underwent a standardized prospective protocol that included a general clinical evaluation, and evaluations by a sleep specialist and psychiatrist.
Subjects who had experienced chronic psychiatric disorders, alcoholism, drug abuse, intake of psychotropic medications (including hypnotic and stimulant agents), unstable medical regimens, circadian rhythm
Subjects
The study included 135 male subjects. The mean (± SD) age was 52 ± 12.1 years, the mean body mass index (BMI) was 27.8 ± 5.6 kg/m2, the mean AHI was 48.7 ± 26.8 events per h, the mean BDI was 8.0 ± 5.9, 60 subjects (44.4%) reported symptoms of esophageal reflux, 62 subjects (45.9%) reported more than one nightly episode of nocturia, and 25 patients (18.5%) received antihypertensive medication. All subjects had a drivers license and drove at least weekly. Twenty-five subjects (18.5%) reported
ACKNOWLEDGMENT
We thank Stephen Brooks, MD, for his editing of the manuscript.
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This work was part of a thesis by Dr. Gonsalves fulfilling the requirements for a Masters degree in Mental Health from the Sleep Research Center of the National Heart, Lung, and Blood Institute of the National Institutes of Health.
Dr. Guilleminault was the recipient of an academic award from the Sleep Research Center, the National Heart, Lung, and Blood Institute, the National Institutes of Health.
Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (e-mail: [email protected]).