Chest
Volume 128, Issue 4, Supplement, October 2005, Page 261S
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Poster Presentations
HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN PATIENTS WITH ALPHA1-ANTITRYPSIN (AAT) DEFICIENCY AND EFFECT OF AUGMENTATION THERAPY: PRELIMINARY RESULTS

https://doi.org/10.1378/chest.128.2.690Get rights and content

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Abstract

PURPOSE: AAT deficiency (AATD), a common genetic disorder which predisposes subjects to early onset emphysema, has been associated with significant decrease in HRQoL over time. Chronic AAT augmentation therapy slows the progression of emphysema, however, its effect on HRQoL has not been clearly delineated. The purpose of our study is to evaluate HRQoL in AAT deficient patients receiving augmentation therapy and to compare the HRQoL scores of AAT deficient patients to the general population.

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