Chest
Diffuse Pneumonitis Due to Adenovirus Type 21 in a Civilian
Section snippets
CASE REPORT
A 21-year-old male college student in excellent health developed rhinorrhea, cough, fever, malaise, and blood streaked sputum in May 1978. He was admitted to his college infirmary on the fifth day of illness and treated with orally administered erythromycin. Three days later, he was transferred to our hospital because of progressively severe respiratory distress. The patient had no history of lung disease, drug use, or trauma.
On examination, the patient was cyanotic and in acute respiratory
DISCUSSION
Serious childhood disease has been associated with adenovirus types 3, 7, and 21.1 Large epidemics have been reported in China.2 Polynesians in New Zealand3 and Indians and Metis in central Canada1 seem to be particularly susceptible. The mortality rate has approached 10 percent in native children from Canada. Acute pathologic features include inflammation of bronchi, bronchiolitis, and bronchopneumonia.8 Residual pulmonary abnormalities have been found in more than one-half of the survivors.1,
ACKNOWLEDGMENT
Dr. Allyn Ley, Gannett Medical Clinic, Ithaca, New York referred the patient to us and Mrs. Margaret Aldrich helped in preparing this manuscript.
REFERENCES (15)
- et al.
Fatal disseminated adenovirus infection in a renal transplant recipient
Am J Med
(1975) - et al.
Type 3 adenoviral pneumonia occurring in a respiratory intensive care unit
Chest
(1978) - et al.
Severe viral pneumonia in young adults: therapy with continuous positive airway pressure
Chest
(1976) - et al.
Recognition and treatment of adult respiratory distress syndrome secondary to viral interstitial pneumonia
Am J Med
(1975) - et al.
Bronchiolitis
Am Rev Respir Dis
(1978) Adenovirus pneumonia epidemic among Peking infants and preschool children in 1958
Chin Med J (Engl)
(1960)- et al.
Bronchopneumonia with serious sequelae in children with evidence of adenovirus type 21 infection
Br Med J
(1969)
Cited by (15)
A human adenovirus species B subtype 21a associated with severe pneumonia
2014, Journal of InfectionCitation Excerpt :The HAdV-B21 prototype was isolated in 1956 from an eye swab sampled during an investigation of trachoma in Saudi Arabia.2 Later studies showed an association of HAdV-B21 with upper and lower respiratory tract infections.3–7 Using immunological methods and characterization by restriction enzyme analysis (REA), several studies described the circulation of multiple HAdV-B21 strains in Europe during the 1960s–1980s in upper and lower respiratory tract infections.8–10
ADENOVIRUSES
2009, Feigin and Cherry's Textbook of Pediatric Infectious Diseases, Sixth EditionMedical treatment of viral pneumonia including SARS in immunocompetent adult
2004, Journal of InfectionSevere Adenovirus type 7 pneumonia in an immunocompetent adult
1997, Annales Francaises d'Anesthesie et de ReanimationSouthwestern Internal Medicine Conference: Pneumonias in adults due to mycoplasma, chlamydiae, and viruses
1987, American Journal of the Medical SciencesClinical manifestations and radiologic findings in adenovirus respiratory outbreak in Isfahan dastgerd prison, Iran, 2012
2016, Journal of Isfahan Medical School