Skip to main content
Log in

B. Evaluation techniques

Journal of Molecular Neuroscience Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Aubourg P., Adamsbaum C., Lavallard Rousseau M. C., et al. (1993) A two-year trial of oleic and erucic acids ("Lorenzo’s oil") as treatment for adrenomyeloneuropathy. N. Engl. J. Med. 329, 745–752.

    Article  PubMed  CAS  Google Scholar 

  • Edwin D., Speedie L. J., Köhler W., et al. (1996) Cognitive and brain magnetic resonance imaging findings in adrenomyeloneuropathy. Ann. Neurol. 40, 675–678.

    Article  PubMed  CAS  Google Scholar 

  • Gärtner J., Braun A., Holzinger A., et al. (1998) Clinical and genetic aspects of X-linked adrenoleukodystrophy. Neuropediatrics 29, 3–13.

    Article  PubMed  Google Scholar 

  • Kaplan P. W., Tusa R. J., Shankroff J., et al. (1993) Visual evoked potentials in adrenoleukodystrophy: A trial with glycerol trioleate and Lorenzo oil. Ann. Neurol. 34, 169–174.

    Article  PubMed  CAS  Google Scholar 

  • Kok F., Neumann S., Sarde C. O., et al. (1995) Mutational analysis of patients with X-linked adrenoleukodystrophy. Hum. Mutat. 6, 104–115.

    Article  PubMed  CAS  Google Scholar 

  • Korenke G. C., Hunneman D. H., Köhler J., et al. (1995) Glyceroltrioleate/glyceroltrierucate therapy in 16 patients with X-chromosomal adrenoleukodystrophy/adrenomyeloneuropathy: effect on clinical, biochemical and neurophysiological parameters. Eur. J. Pediatr. 154, 64–70.

    Article  PubMed  CAS  Google Scholar 

  • Kumar A. J., Köhler W., Kruse B., et al. (1995) MR findings in adult-onset adrenoleukodystrophy. Am. J. Neuroradiol. 16, 1227–1237.

    PubMed  CAS  Google Scholar 

  • Kurtzke J. F. (1970) Neurologic impairment in multiple sclerosis and the disability Status Scale. Acta. Neurol. Scand. 46, 493–512.

    Article  PubMed  CAS  Google Scholar 

  • Loes D. J., Hite S., Moser H., et al. (1994) Adrenoleukody-strophy: A scoring method for brain MR observations. Am. J. Neuroradiology 15, 1761–1766.

    CAS  Google Scholar 

  • Moser H. W. (1997) Adrenoleukodystrophy: Phenotype, genetics, pathogenesis and therapy. Brain 120, 1485–1508.

    Article  PubMed  Google Scholar 

  • Moser H. W. and Moser A. B. (1989) Adrenoleukodystrophy (X-linked), in The Metabolic Bases of Inherited Disease, 6th ed. (Scriver C. R., Beaudet A. L., Sly W. S., et al., eds.), McGraw Hill, New York, pp. 1511–1532.

    Google Scholar 

  • Moser H. W., Köhler W., Borel J., et al. (1995) The many faces of X-linked adrenoleukodystrophy: Implications for pathogenesis and the evaluation of therapy, in Functions and Biogenesis of Peroxisomes in Relation to Human Disease (Wanders R. J. A., Schutgens R. B. H., Tabak H. F., eds.), North-Holland, Amsterdam, pp. 227–246.

    Google Scholar 

  • Singh I., Kahn M., Key L., et al. (1998) Lovastatin for X-linked adrenoleukodystrophy. N. Engl. J. Med. 339, 702,703.

    Article  PubMed  CAS  Google Scholar 

  • Uziel G., Bertini E., Bardelli P., et al. (1991) Experience on therapy of adrenoleukodystrophy and adrenomyeloneuropathy. Dev. Neurosci. 13, 274–279.

    PubMed  CAS  Google Scholar 

References

  • van der Knaap M.S. and Valk J. (1995) Magnetic Resonance of Myelin, Myelination and Myelin Disorders, 2nd ed. Springer, Heidelberg.

    Google Scholar 

  • van der Knaap M. S., Valk J., de Neeling N., and Nauta J. J. P. (1991) Pattern recognition in magnetic resonance imaging of white matter disorders in children and young adults. Neuroradiology 33, 478–493.

    Article  PubMed  Google Scholar 

References

  • Aubourg P., Sellier N., Chaussain J. L., and Kalifa G. (1989) MRI detects cerebral involvement in neurologically asymptomatic patients with adrenoleukodystrophy. neurology 39, 1619–1621.

    PubMed  CAS  Google Scholar 

  • Basser P. J. and Pierpaoli C. (1996) Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. J. Magn. Reson. B. 111, 209–219.

    Article  PubMed  CAS  Google Scholar 

  • Basser P. J., Mattiello J., and LeBihan D. (1994a) Estimation of the effective self-diffusion tensor from the NMR spin echo. J. Magn. Reson. B. 103, 247–254.

    Article  PubMed  CAS  Google Scholar 

  • Basser P. J., Mattiello J., and LeBihan D. (1994b) MR diffusion tensor spectroscopy and imaging. Biophys. J. 66, 259–267.

    PubMed  CAS  Google Scholar 

  • Beaulieu C. and Allen P.S. (1994) Water diffusion in the giant axon of the squid: Implications for diffusion-weighted MRI of the nervous system. Magn. Reson. Med. 32, 579–583.

    Article  PubMed  CAS  Google Scholar 

  • Carr H. Y. and Purcell H. Y. (1954) Effects of diffusion on free precession in nuclear magnetic resonance experiments. Phys. Rev. 94, 630–638.

    Article  CAS  Google Scholar 

  • Chun T., Ulug A. M., and van Zijl P. C. M. (1998) Single-shot diffusion-weighted trace imaging on a clinical scanner. Magn. Reson. Med. 40, 622–628.

    Article  PubMed  CAS  Google Scholar 

  • Hajnal J. V., Bydder G. M., and Young I. R. (1994) Use of fluid attenuated inversion recovery sequence in magnetic resonance imaging [letter; comment]. Lancet 344, 8939,8940.

    Article  Google Scholar 

  • Kruse B., Barker P. B., van Zijl P. C., Duyn J. H., Moonen C. T., and Moser H. W. (1994) Multislice proton magnetic resonance spectroscopic imaging in X-linked adrenoleukodystrophy. Ann. Neurol. 36, 595–608.

    Article  PubMed  CAS  Google Scholar 

  • Le Bihan D., Breton E., and Lallemand D. (1986) MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology 161, 401–407.

    PubMed  Google Scholar 

  • Makris N., Worth A. J., Sorensen A. G., Papadimitriou G. M., Wu 0., Reese T. G., et al. (1997) Morphometry of in vivo human white matter association pathways with diffusion-weighted magnetic resonance imaging. Ann. Neurol. 42, 951–962.

    Article  PubMed  CAS  Google Scholar 

  • Melhem E. R., Breiter S. N., Ulug A. M., Raymond G. V., and Moser H. W. (1996) Improved tissue characterization in adrenoleukodystrophy using magnetization transfer imaging. Am. J. Roentgenol. 166, 689–695.

    CAS  Google Scholar 

  • Moonen C. T., Pekar J., deVleeschouwer MH, van Gelderen P., van Zijl P. C., and DesPres D. (1991) Restricted and anisotropic displacement of water in healthy cat brain and in stroke studied by NMR diffusion imaging. Magn. Reson. Med. 19, 327–332.

    Article  PubMed  CAS  Google Scholar 

  • Mori S. and van Zijl P. C. M. (1995) Diffusion weighting by the trace of the diffusion tensor within a single scan. Magn. Reson. Med. 33, 41–52.

    Article  PubMed  CAS  Google Scholar 

  • Mori S., Crain B. J., Chacko V. P., and van Zijl P. C. M. Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann. Neurol. (in press).

  • Moseley M. E., Cohen Y., Kucharczyk J., Mintorovitch J., Asgari H. S., Wendland M. F., et al. (1990) Diffusion-weighted MR imaging of anisotropic water diffusion in cat central nervous system. Radiology 176, 439–445.

    PubMed  CAS  Google Scholar 

  • Pierpaoli C., Jezzard P., Basser P. J., Bamett A., and Di Chiro G. (1996) Diffusion tensor MR imaging of the human brain. Radiology 201, 637–648.

    PubMed  CAS  Google Scholar 

  • Pierpaoli C., Choi B., Schiffmann R., and Di Chiro G. (1997) Diffusion tensor MRI in Pelizaeus-Merzbacher disease [abstract], in Book of ISMRM, 5th Scientific Meeting Vancouver, B.C., p. 664.

  • Stejskal E. O. and Tanner J. E. (1965) Spin diffusion measurements: Spin echoes in the presence of a time-dependent field gradient. J. Chem. Phys. 42, 288–292.

    Article  CAS  Google Scholar 

  • Ulug A. M. and van Zijl P. C. M. (1997) Orientation-independent diffusion tensor imaging of the human brain. J. Mag. Reson. I.

  • Wimberger D. M., Roberts T. P., Barkovich A. J., Prayer L. M., Moseley M. E., and Kucharczyk J. (1995) Identification of “premyelination” by diffusion-weighted MRI. J. Comput. Assist. Tomogr. 19, 28–33.

    Article  PubMed  CAS  Google Scholar 

  • Wolff S. D. and Balaban R. S. (1994) Magnetization transfer imaging: Practical aspects and clinical applications. Radiology 192, 593–599.

    PubMed  CAS  Google Scholar 

References

  • Cady E. B., Dawson M. J., Hope P. L., Tofts P. S., de Costello A. M., Delpy D. T., et al. (1983) Non-invasive investigation of cerebral metabolism in newborn infants by phosphorus nuclear magnetic resonance spectroscopy. Lancet 1, 1059.

    Article  PubMed  CAS  Google Scholar 

  • Confort-Gouny S., Vion-Dury J., Chabrol B., Nicoli F., and Cozzone P.J. (1995) Localized proton magnetic resonance spectroscopy in X-linked adrenoleukodystrophy. Neuroradiology 37, 568.

    Article  PubMed  CAS  Google Scholar 

  • Ernst T., Kreis R., and Ross B. D. (1993) Absolute quantitation of water and metabolites in the human brain. Part I: compartments and water. J. Magn. Reson. 102, 1.

    Article  CAS  Google Scholar 

  • Kreis R., Ernst T., and Ross B. D. (1993) Absolute quantitation of water and metabolites in the human brain. Part II: metabolite concentrations. J. Magn. Reson. 102, 9.

    Article  CAS  Google Scholar 

  • Tzika A. A., Ball W. S., Vigneron D. B., Dunn R. S., Nelson S. J., and Kirks D. R. (1993) Childhood adrenoleukodystrophy: assessment with proton MR spectroscopy. Radiology 189, 467.

    PubMed  CAS  Google Scholar 

References

  • Bluml S., McComb J. G., and Ross B. D. (1997) Differentiation between cortical atrophy and hydrocephalus using 1H MRS. Magn. Reson. Med. 37, 395–403.

    Article  PubMed  CAS  Google Scholar 

  • Kreis R., Ernst T., and Ross B. D. (1993a) Absolute quantitation of water and metabolites in the human brain. Part II: Metabolite concentrations. J. Magn. Reson. 102, 9–19.

    CAS  Google Scholar 

  • Kreis R., Ernst T., and Ross B. D. (1993b) Development of the human brain: In vivo quantification of metabolite and water content with proton MRS. Magn Reson. Med. 30, 424–437.

    Article  PubMed  CAS  Google Scholar 

  • Tan J., Bluml S., Hoang T., Dubowitz D., Mevenkamp G., and Ross B. (1998) Lack of effect of oral choline supplement of the concentrations of choline metabolites in human brain. Magn. Reson. Med. 39.

  • van der Knaap M. S., van der Grond J., van Rijen P. C., Faber J. A. J., Valk J., and Willemse K. (1990) Age-dependent changes in localized proton and phosphorus MR spectroscopy of the brain. Radiology 176, 509–513.

    PubMed  Google Scholar 

References

  • Giesser B. S., Kurtzberg D., Vaughan H. G., Arezzo J. C., Aisen M. L., Smith C. R., et al. (1987) Trimodal evoked potentials compared with magnetic resonance imaging in the diagnosis of Multiple Scelerosis. Arch. Neurol. 44, 281–284.

    PubMed  CAS  Google Scholar 

  • Honig L. S., Ramsay R. E., and Sheremata W. A. (1992) Eventrelated potential P300 in Multiple Sclerosis: Relation to magnetic resonance imaging and cognitive impairment. Arch. Neurol. 49, 44–50.

    PubMed  CAS  Google Scholar 

  • Molfese D. L. and Molfese V. J. (1997) Discrimination of language skills at five years of age using event-related potentials recorded at birth. Dev. Neuropsychology 13(2), 135–156.

    Article  Google Scholar 

  • Nuwer M. R., Packwood J. W., Myers L. W., and Ellison G. W. (1987) Evoked potentials predict the clinical changes in a multiple sclerosis drug study. Neurology 37, 1754–1761.

    PubMed  CAS  Google Scholar 

  • Slater J. D., Wu F. Y., Honig L. S., Ramsay R. E., and Morgan R. (1994) Neural network analysis of the P300 event-related potential in multiple sclerosis. Electroencephalogr. Clin. Neurophysiol. 90, 114–122.

    Article  PubMed  CAS  Google Scholar 

References

  • Aubourg P., Blanche S., Jambaque I., et al. (1990) Reversal of early neurologic and neuroradiologic manifestations of X-linked adrenoleukodystrophy by BM Tation. N. Engl. J. Med. 322, 1860–1866.

    Article  PubMed  CAS  Google Scholar 

  • Gärtner J., Braun A., Holzinger A., et al. (1998) Clinical and genetic aspects of X-linked adrenoleukodystrophy. Neuropediatrics 29, 3–13.

    Article  PubMed  Google Scholar 

  • Krivit W., Lockman L. A., Watkins P. A., Hirsch J., and Shapiro E. G. (1995) The future for treatment by bone marrow transplantation for adrenoleukodystrophy, metachromatic leukodystrophy, globoid cell leukodystrophy and Hurler syndrome. J. Inherited Metab. Dis. 18, 398–412.

    Article  PubMed  CAS  Google Scholar 

  • Lilford R. J., Thomton J. G., and Braunholtz D. (1995) Clinical trials and rare diseases: a way out of a conundrum. Br. Med. J. 311, 1621–1625.

    CAS  Google Scholar 

  • Shapiro E. G., Lockman L. A., Balthazor M., and Krivit W. (1995) Neuropsychological outcomes of several storage diseases with and without BMTation. J. Inherited Metab. Dis. 18, 413–419.

    Article  PubMed  CAS  Google Scholar 

References

  • Cohen P. J. (1998) The placebo is not dead: three historical vignettes. IRB: a Rev. Hum. Subjects Res. 20, 6–8.

    Google Scholar 

  • Fetting J. H., Siminoff L. A., Piantadosi S., Abeloff M. D., Damron D. J., and Sarsfield A. M. (1990) Effect of patients’ expectations of benefit with standard breast cancer adjuvant chemotherapy on participation in a randomized clinical trial: a clinical vignette study. J. Clin. Oncol. 8(9), 1476–1482.

    PubMed  CAS  Google Scholar 

  • Kass N., Sugarman J., Faden R., and Schoch-Spana M. (1996) Trust: the fragile foundation of contemporary biomedical research. The Hastings Center Report 26, 25–29.

    Article  PubMed  CAS  Google Scholar 

  • Rajagopal S., Goodman P. J., and Tannuck I. F. (1994) Adjuvant chemotherapy for breast cancer: discordance between physicians’ perception of benefit and the results of clinical trials. J. Clin. Oncol. 12(6), 1296–1304.

    PubMed  CAS  Google Scholar 

  • National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, “The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research.” April 18, 1979.

Download references

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Moser, H.W. B. Evaluation techniques. J Mol Neurosci 13, 247–267 (1999). https://doi.org/10.1385/JMN:13:3:247

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1385/JMN:13:3:247

Keywords

Navigation