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01.04.2007 | Leading Article

Satraplatin in Hormone-Refractory Prostate Cancer and Other Tumour Types

Pharmacological Properties and Clinical Evaluation

verfasst von: Dr Mark J. McKeage

Erschienen in: Drugs | Ausgabe 6/2007

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Abstract

Satraplatin is the first orally administered platinum drug to be evaluated in the clinic. Oral satraplatin plus prednisone improved progression free survival significantly relative to prednisone alone in patients with hormone-refractory prostate cancer in a randomised study. Furthermore, single-agent satraplatin has demonstrated activity in ovarian cancer and small cell lung cancer similar to that observed with single-agent cisplatin or carboplatin. In >600 treated patients, satraplatin was generally well tolerated and the most common adverse event was non-cumulative myelosuppression.

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Titel: Satraplatin in Hormone-Refractory Prostate Cancer and Other Tumour Types
Pharmacological Properties and Clinical Evaluation
verfasst von: Dr Mark J. McKeage
Publikationsdatum: 01.04.2007
Verlag: Springer International Publishing
Erschienen in: Drugs / Ausgabe 6/2007
Print ISSN: 0012-6667
Elektronische ISSN: 1179-1950
DOI: https://doi.org/10.2165/00003495-200767060-00003

Springer Medizin

Abstract

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