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Community Pharmacy, Disease State Management, and Adherence to Medication

A Review

  • Review Article
  • Published:
Disease Management & Health Outcomes

Abstract

Community pharmacists are well trained healthcare professionals who are able and willing to implement extended medication services. In the past decade, a plethora of pharmaceutical care and pharmacy-based disease management programs have been developed and trialed for delivery in primary care settings. Since suboptimal medication adherence is a feature of chronic illness, it is important to review the success of disease management interventions targeting adherence. This review focuses on the programs that were developed for asthma, diabetes mellitus, and cardiovascular disease in community pharmacies and that either targeted medication adherence or reported it as an outcome.

Studies of community pharmacy-based disease management programs targeting adherence in patients with asthma, diabetes mellitus, and cardiovascular disease have demonstrated positive effects on clinical outcomes other than adherence. A variety of adherence-measuring methods were used in these studies, ranging from patient self-report and qualitative descriptions to electronic recording. In most cases, strategies to improve adherence were part of a complex intervention, and a direct link between the intervention and adherence improvement could not be demonstrated. At this stage, it is not known what type of intervention results in the greatest impact and most sustained improvement in medication adherence. Future studies should provide evidence for the impact of adherence on not only clinical and patient-centered outcomes, but also economic outcomes. Evidence for the sustainability of the outcomes should be a priority for future research.

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References

  1. Benrimoj CSI, Frommer MS. Community pharmacy in Australia. Aust Health Rev 2004; 28: 238–46

    Article  PubMed  Google Scholar 

  2. Royal Pharmaceutical Society of Great Britain. Patient counselling audit. 2006 [online]. Available from URL: http://www.rpsgb.org/pdfs/pat_coun.pdf [Accessed 2007 Apr 11]

  3. Chen TF, Crampton M, Krass I, et al. Collaboration between community pharmacists and GPs in innovative clinical services: a conceptual model. J Soc Admin Pharm 1999; 16: 134–44

    Google Scholar 

  4. Hepler CD, Strand LM. Opportunities and responsibilities in pharmaceutical care. Am J Hosp Pharm 1990; 47: 533–43

    PubMed  CAS  Google Scholar 

  5. Scott IA, Denaro CP, Bennett CJ, et al. Achieving better in-hospital and afterhospital care of patients with acute cardiac disease. Med J Aust 2004; 180 (10 Suppl.): S83–8

    PubMed  Google Scholar 

  6. Sabate E, editor. Adherence to long term therapies: evidence for action. Geneva: World Health Organisation, 2003 [online]. Available from URL: http://www.who.int/chp/knowledge/publications/adherencerep.pdf [Accessed 2008 Apr 15]

    Google Scholar 

  7. Horne R. Implications for asthma treatment compliance, adherence and concordance. Chest 2006; 130: 65–72

    Article  Google Scholar 

  8. Kripalani S, Yao X, Haynes B. Interventions to enhance medication adherence in chronic conditions. Arch Intern Med 2007; 167: 540–9

    Article  PubMed  Google Scholar 

  9. Mehuys E, Van Bortel L, De Bolle L, et al. Effectiveness of pharmacist intervention for asthma control improvement. Eur Respir J 2008; 31: 790–9

    Article  PubMed  CAS  Google Scholar 

  10. Holland R, Brooksby I, Lenaghan E, et al. Effectiveness of visits from community pharmacists for patients with heart failure: HeartMed randomized controlled trial. BMJ 2007; 334: 1098. Epub 2007 Apr 23

    Article  PubMed  Google Scholar 

  11. Mangiapane S, Schulz M, Mühlig S, et al. Community pharmacy-based pharmaceutical care for asthma patients. Ann Pharmacother 2005; 39: 1817–22

    Article  PubMed  Google Scholar 

  12. Armour C, Bosnic-Anticevich S, Brillant M, et al. Pharmacy asthma care program (PAC) improves outcomes for patients in the community. Thorax 2007; 62: 496–502

    Article  PubMed  Google Scholar 

  13. Cordina M, McElnay JC, Hughes CM. Assessment of a community pharmacybased program for patients with asthma. Pharmacotherapy 2001; 21: 1196–203

    Article  PubMed  CAS  Google Scholar 

  14. Smith L, Bosnic-Anticevich SZ, Mitchell B, et al. Treating asthma with a self-management model of illness behaviour in an Australian community pharmacy setting. Soc Sci Med 2007; 64: 1501–11

    Article  PubMed  Google Scholar 

  15. Weinberger M, Murray MD, Marrero DG, et al. Effectiveness of pharmacist care for patients with reactive airways disease: a randomized controlled trial. JAMA 2002; 288: 1594–602

    Article  PubMed  Google Scholar 

  16. Armour C, Taylor S, Hourihan F, et al. Implementation and evaluation of Australian pharmacists’ diabetes care services. J Am Pharm Assoc 2004; 44: 455–66

    Article  Google Scholar 

  17. Krass I, Armour CL, Mitchell B, et al. The Pharmacy Diabetes Care Program: assessment of a community pharmacy diabetes service model in Australia. Diabet Med 2007; 24: 677–83

    Article  PubMed  CAS  Google Scholar 

  18. Blenkinsopp A, Phelan M, Bourne J, et al. Extended adherence support by community pharmacists for patients with hypertension: a randomised controlled trial. Int J Pharm Pract 2000; 8: 165–75

    Article  Google Scholar 

  19. Gordois A, Armour C, Brillant M, et al. Cost-effectiveness analysis of a pharmacy asthma care program in Australia. Dis Manage Health Outcomes 2007; 15: 1–15

    Article  Google Scholar 

  20. Taylor SJ, Milanova T, Hourihan F, et al. Cost-effectiveness analysis of a community pharmacist initiated disease state management service for type 2 diabetes mellitus. Int J Pharm Pract 2005; 13: 33–40

    Article  Google Scholar 

  21. Krass I, Armour CL, Mitchell B, et al. The Pharmacy Diabetes Care Program: final report to The Commonwealth Department of Health and Ageing as part of the Third Community Pharmacy Research and Development Grants Program. 2005 Apr [online]. Available from URL: http://www.guild.org.au/uploadedfiles/Research_and_Development_Grants_Program/Projects/2002-518_fr.pdf [Accessed 2007 Aug 30]

  22. Saini B, Filipovska J, Bosnic-Anticevich S, et al. An evaluation of a community pharmacy-based rural asthma management service. Aust J Rural Health 2008: 16: 100–8

    Article  PubMed  Google Scholar 

  23. Saini B, Krass I, Armour C. Development, implementation, and evaluation of a community pharmacy-based asthma care model. Ann Pharmacother 2004; 38: 1954–60

    Article  PubMed  Google Scholar 

  24. Blumi M, McKenney J, Cziraky M. Pharmaceutical care services and results in project ImPACT: hyperlipidaemia. J Am Pharm Assoc 2000; 40: 157–65

    Google Scholar 

  25. Kritikos V, Armour CL, Bosnic-Anticevich SZ. Interactive small-group asthma education in the community pharmacy setting: a pilot study. J Asthma 2007; 44: 57–64

    Article  PubMed  Google Scholar 

  26. Svarstad BL, Chewning BA, Sleath BL, et al. The Brief Medication Questionnaire: a tool for screening patient adherence and barriers to adherence. Patient Educ Counsel 1999; 37: 113–24

    Article  CAS  Google Scholar 

  27. Horne R, Weinman J. Self-regulation and self-management in asthma: exploring the role of illness perceptions and treatment beliefs in explaining non-adherence to preventer medication. Psychol Health 2002; 17: 17–32

    Article  Google Scholar 

  28. Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self reported measure of medication adherence. Med Care 1986; 24: 67–74

    Article  PubMed  CAS  Google Scholar 

  29. Cranor CW, Christensen DB. The Asheville Project: short-term outcomes of a community pharmacy diabetes care program. J Am Pharm Assoc 2003; 43: 149–59

    Article  Google Scholar 

  30. Wermeille J, Bennie M, Brown I, et al. Pharmaceutical care model for patients with type 2 diabetes: integration of the community pharmacist into the diabetes team. A pilot study. Pharm World Sci 2004; 26: 18–25

    Article  PubMed  Google Scholar 

  31. Berringer R, Shibley MC, Cary CC, et al. Outcomes of a community pharmacybased diabetes monitoring program [comment]. J Am Pharm Assoc 1999; 39: 791–7

    CAS  Google Scholar 

  32. MacDonough RP, Doucette WR. Drag therapy management: an empirical report of drug therapy problems, pharmacists interventions, and results of pharmacists actions. J Am Pharm Assoc 2003; 43: 511–8

    Article  Google Scholar 

  33. Bouvy ML, Heerdink ER, Urquhart J, et al. Effect of a pharmacist-led intervention on diuretic compliance in heart failure patients: a randomized controlled study. J Card Fail 2003; 9: 404–11

    Article  PubMed  Google Scholar 

  34. Tsuyuki RT, Olson LO, Dubyk AM, et al. Effect of community pharmacist intervention on cholesterol levels in cardiovascular patients of high risk of cardiovascular events: the second study of cardiovascular risk intervention by pharmacists (SCRIP-plus). Am J Med 2004; 116: 130–3

    Article  PubMed  Google Scholar 

  35. Chabot I, Moisan J, Gregoire JP, et al. Pharmacist intervention program for control of hypertension. Ann Pharmacother 2003; 37: 1186–93

    Article  PubMed  Google Scholar 

  36. Elliott RA, Barber N, Home R. Cost-effectiveness of adherence-enhancing interventions: a quality assessment of the evidence. Ann Pharmacother 2005; 39: 508–15

    Article  PubMed  Google Scholar 

  37. Van Wijk BLG, Klungel OH, Heerdink ER, et al. Effectiveness of interventions by community pharmacists to improve patient adherence to chronic medication: a systematic review. Ann Pharmacother 2005; 39: 319–28

    Article  PubMed  Google Scholar 

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Acknowledgments

No sources of funding were used to assist in the preparation of this review. The authors have no conflicts of interest that are directly relevant to the content of this review.

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Armour, C.L., Smith, L. & Krass, I. Community Pharmacy, Disease State Management, and Adherence to Medication. Dis-Manage-Health-Outcomes 16, 245–254 (2008). https://doi.org/10.2165/00115677-200816040-00005

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