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Erschienen in: Pediatric Drugs 6/2008

01.11.2008 | Therapy In Practice

Treatment Strategies for Methicillin-Resistant Staphylococcus aureus Infections in Pediatrics

verfasst von: Dr Jason G. Newland, Gregory L. Kearns

Erschienen in: Pediatric Drugs | Ausgabe 6/2008

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Abstract

Staphylococcus aureus is an important pathogen that frequently causes clinical disease in children. A wide array of illnesses can be caused by this common pathogen ranging from non-invasive skin infections to severe, life-threatening sepsis. Additionally, as antibacterials have been used to eradicate S. aureus, it has developed resistance to these important therapeutic agents. Methicillin-resistant S. aureus (MRSA) has become an increasing problem in pediatric patients over the past decade. In this review, we discuss the epidemiology, pathogenesis, and treatment options available in treating MRSA infections in children. Specifically, we address the importance of abscess drainage in the treatment of skin and soft tissue infections, the most common clinical manifestation of MRSA infections, and highlight the various agents that are available for treating this common infection. In severe, life-threatening invasive MRSA infections the primary therapeutic option is vancomycin. In cases of MRSA toxic shock syndrome the addition of clindamycin is necessary. In other invasive MRSA infections, such as pneumonia and musculoskeletal infections, the empiric treatment of choice is clindamycin. Finally, newer agents and additional treatment options are discussed.
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Metadaten
Titel
Treatment Strategies for Methicillin-Resistant Staphylococcus aureus Infections in Pediatrics
verfasst von
Dr Jason G. Newland
Gregory L. Kearns
Publikationsdatum
01.11.2008
Verlag
Springer International Publishing
Erschienen in
Pediatric Drugs / Ausgabe 6/2008
Print ISSN: 1174-5878
Elektronische ISSN: 1179-2019
DOI
https://doi.org/10.2165/0148581-200810060-00004

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