Pulmonary Infiltration with Eosinophilia and Increased Serum Levels of Squamous Cell Carcinoma-Related Antigen and Neuron Specific Enolase

Osamu SAKITO; Jun-ichi KADOTA; Shigeru KOHNO; Naomi ITOH; Osamu TAKAHARA; Kohei HARA

doi:10.2169/internalmedicine.33.550

Osamu SAKITO, Jun-ichi KADOTA, Shigeru KOHNO, Naomi ITOH, Osamu TAKAHARA, Kohei HARA

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Keywords: tumor marker, bronchoalveolar lavage, corticosteroid therapy, amoxicillin

JOURNAL FREE ACCESS

1994 Volume 33 Issue 9 Pages 550-553

DOI https://doi.org/10.2169/internalmedicine.33.550

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Abstract

We report a case of pulmonary infiltration with eosinophilia (PIE), associated with increased serum levels of squamous cell carcinoma-related antigen (SCC) and neuron specific enolase (NSE). The diagnosis of PIE was confirmed by examination of bronchoalveolar lavage fluid and specimens of transbronchial lung biopsy. It was suggested that PIE was probably induced by a course of amoxicillin for a sore throat. Corticosteroid therapy resulted in clinical improvement of symptoms, resolution of pulmonary infiltrates on chest roentgenogram and reduction in serum levels of SCC and NSE.
(Internal Medicine 33: 550-553, 1994)

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