Corticosteroid Refractory Radiation Pneumonitis that Remarkably Responded to Cyclosporin A

Tomie MURAOKA; Shuji BANDOH; Jiro FUJITA; Atsushi HORIIKE; Tomoya ISHII; Yasunori TOJO; Akihito KUBO; Toshihiko ISHIDA

doi:10.2169/internalmedicine.41.730

Tomie MURAOKA, Shuji BANDOH, Jiro FUJITA, Atsushi HORIIKE, Tomoya ISHII, Yasunori TOJO, Akihito KUBO, Toshihiko ISHIDA

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Keywords: lung cancer, steroid therapy, immunosuppressive agent, surfactant protein A, surfactant protein D

JOURNAL FREE ACCESS

2002 Volume 41 Issue 9 Pages 730-733

DOI https://doi.org/10.2169/internalmedicine.41.730

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Abstract

Radiation therapy is commonly used for the treatment of lung cancer. However, radiation pneumonitis frequently occurs as a complication of the radiation therapy. Although corticosteroids are widely used for the treatment of radiation pneumonitis, they are not always effective. In this report, we used cycosporin A in the treatment of a patient suffering from steroid-refractory radiation pneumonitis. To our knowledge, this is the first report in which cyclosporin A was successfully used in the treatment of radiation pneumonitis.
(Internal Medicine 41: 730-733, 2002)

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