Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
ORIGINAL ARTICLES
Pure Red Cell Aplasia Associated with Good's Syndrome Accompanied by Decreased Stem Cell Factor Production in the Bone Marrow
Kageaki Kuribayashi, Akihito Fujimi, Masayoshi Kobune, Rishu Takimoto, Shohei Kikuchi, Satoshi Iyama, Junji Kato, Yoshiro Niitsu, Naoki Watanabe
Author information
Keywords: pure red cell aplasia, stem cell factor, thymoma, Good's syndrome, hypogammaglobulinemia, cyclosporine-A
JOURNAL OPEN ACCESS

2010 Volume 49 Issue 5 Pages 377-382

Details
Download PDF (1004K)
Download citation RIS

(compatible with EndNote, Reference Manager, ProCite, RefWorks)

BIB TEX

(compatible with BibDesk, LaTeX)

Text
How to download citation
Contact us
Abstract

A 79-year-old Japanese woman diagnosed with pure red cell aplasia (PRCA) associated with thymoma and hypogammaglobulinemia (Good's syndrome) was successfully treated with cyclosporine-A after a thymectomy. We further studied the etiology of this case. A burst-forming unit erythroid (BFU-E) assay with SCF restored erythropoiesis in vitro. SCF production was reduced in bone marrow stromal cells; however, it was restored in vitro and in vivo after cyclosporine-A treatment.

Content from these authors
© 2010 by The Japanese Society of Internal Medicine
Previous article Next article
Favorites & Alerts

Recently viewed articles
Predecessor

Japanese Journal of Medicine

Share this page
feedback
 Top