Association of Graves' Disease with Evans' Syndrome in a Patient with IgA Nephropathy

Keiichi IKEDA; Yukio MARUYAMA; Michiko YOKOYAMA; Naohiko KATO; Hiroyasu YAMANOTO; Yoshihiko KAGUCHI; Masaaki NAKAYAMA; Takashi SHIMADA; Katsuyoshi TOJO; Tetsuya KAWAMURA; Tatsuo HOSOYA

doi:10.2169/internalmedicine.40.1004

Keiichi IKEDA, Yukio MARUYAMA, Michiko YOKOYAMA, Naohiko KATO, Hiroyasu YAMANOTO, Yoshihiko KAGUCHI, Masaaki NAKAYAMA, Takashi SHIMADA, Katsuyoshi TOJO, Tetsuya KAWAMURA, Tatsuo HOSOYA

Author information

Keiichi IKEDA
the Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine
Yukio MARUYAMA
the Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine
Michiko YOKOYAMA
the Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine
Naohiko KATO
the Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine
Hiroyasu YAMANOTO
the Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine
Yoshihiko KAGUCHI
the Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine
Masaaki NAKAYAMA
the Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine
Takashi SHIMADA
the Division of Hematology and Oncology, Department of Internal Medicine, Jikei University School of Medicine
Katsuyoshi TOJO
the Division of Diabetes and Endocrinology, Department of Internal Medicine, Jikei University School of Medicine
Tetsuya KAWAMURA
the Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine
Tatsuo HOSOYA
the Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine

Keywords: hyperthyroidism, autoimmune hemolytic anemia, idiopathic thrombocytopenic purpura, chronic renal failure

JOURNAL FREE ACCESS

2001 Volume 40 Issue 10 Pages 1004-1010

DOI https://doi.org/10.2169/internalmedicine.40.1004

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Abstract

A 20-year-old woman with IgA nephropathy was admitted to Jikei University Hospital for the treatment of rapid deterioration of renal function after receiving ¹³¹I-therapy against hyperthyroidism on October 23, 1999, and hemodialysis was started. On admission, she was diagnosed as having Evans' syndrome in addition to known Graves' disease. Renal biopsy revealed end-stage renal damage, then, hemodialysis was maintained. Treatment for Evans' syndrome was also started and her general condition gradually improved. The present case implied that "Graves' disease" and "Evans' syndrome" could represent some of the manifestations of an underlying immunological disorder in the patient.
(Internal Medicine 40: 1004-1010, 2001)

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