Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Rheumatic Diseases
A Rare Case of Idiopathic Hypereosinophilic Syndrome Involving the Oral Cavity Associated with the Esophagus and Gastrointestinal Tract
Michi WATANABENoriaki MATSUISyuji HAMADAJiro OHUCHINaoya SHIMOHASHIMasaki KATOHMakoto KUNISAKIYuichi TANABEToshihiko HASHIMOTOKisaku YOSHIDAHideoki URYUHidetaka YAMAMOTO
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JOURNAL OPEN ACCESS

2004 Volume 43 Issue 4 Pages 336-339

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Abstract

We report the rare case of HES involving oral cavity associated with esophagus, and gastrointestinal tract, which we succeeded in diagnosing precisely through a biopsy specimen obtained from the lip. A 64-year-old man had dysphagia, swelling of the oral mucosa and the posterior cervical muscles, accompanied by an abdominal pain and diarrhea. Peripheral blood cell count showed marked eosinophilia. Computed tomography showed thickening of posterior wall of the pharynx, esophagus, and gastrointestinal tract. Histologic specimen obtained from the lower lip demonstrated a moderate infiltration of eosinophils. His clinical condition was improved by oral prednisolone therapy.

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© 2004 by The Japanese Society of Internal Medicine
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