Chronic Myelogenous Leukemia That Occurred Two Years after the Diagnosis of Adult Still’s Disease

Yoshifumi NAKAGAWA; Norihiro FURUSYO; Hiroaki TANIAI; Hideho HENZAN; Takuya TSUCHIHASHI; Jun HAYASHI

doi:10.2169/internalmedicine.44.994

CASE REPORTS

Chronic Myelogenous Leukemia That Occurred Two Years after the Diagnosis of Adult Still’s Disease

Yoshifumi NAKAGAWA, Norihiro FURUSYO, Hiroaki TANIAI, Hideho HENZAN, Takuya TSUCHIHASHI, Jun HAYASHI

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Keywords: chronic myelogenous leukemia, adult Still’s disease, cyclophosphamide, cyclosporine

JOURNAL OPEN ACCESS

2005 Volume 44 Issue 9 Pages 994-997

DOI https://doi.org/10.2169/internalmedicine.44.994

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Abstract

A 25-year-old Japanese man was diagnosed with steroid-resistant Adult Still’s Disease (ASD) in August 2000. No evidence of chronic myelogenous leukemia (CML) had been found during admissions in 2000 and 2001. In August 2002, he was diagnosed with CML with a peripheral white blood count of 69,940/μl and positivity for Philadelphia chromosome and BCR/ABL fusion gene on bone marrow aspiration. No case of CML was reported to develop from ASD. Because a diagnosis of ASD is based on the exclusion of other diseases, we must be cognizant of the possibility of the development of concurrent diseases.

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