Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Subcutaneous Panniculitislike Tcell Lymphoma: Successful Initial Treatment with Prednisolone and Cyclosporin A
Yuka Tsukamoto, Yoshioka Katsunobu, Yoko Omura, Isseki Maeda, Manabu Hirai, Hirofumi Teshima, Yoshio Konishi, Takeshi Inoue, Toshihiko Sato
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Keywords: subcutaneous panniculitislike Tcell lymphoma, hemophagocytosis, cyclosporin A, WeberChristian disease
JOURNAL OPEN ACCESS

2006 Volume 45 Issue 1 Pages 21-24

[Correction] Intern. Med. Vol.45 (2006) No.6 p.410
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Abstract

A case of subcutaneous panniculitislike Tcell lymphoma (SPTCL) is reported. A 27yearold man presented with fever and abdominal swelling. His laboratory examination revealed pancytopenia and liver dysfunction. The diagnosis of SPTCL was made by biopsy based on thickened subcutaneous tissue. In addition, bone marrow specimen showed a hemophagocytosis syndrome (HPS). Methylprednisolone pulse therapy was initiated followed by prednisolone (60 mg/day) and cyclosporin A (150 mg/day). He responded to the treatment and remained asymptomatic for at least for 6 months. Our results suggest that a trial of cyclosporin A is warranted in patients with SPTCL complicated by HPS.

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© 2006 by The Japanese Society of Internal Medicine
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