Sarcoidosis with Acute Recurrent Polyarthritis and Hypercalcemia

Takeo Sato; Tsunehisa Tsuru; Kiyofumi Hagiwara; Kazuhisa Miyashita; Hiroaki Matsuno; Atsuo Goto; Masaru Oritsu; Teruhiko Hamanaka; Osamu Akiyama

doi:10.2169/internalmedicine.45.1521

CASE REPORTS

Sarcoidosis with Acute Recurrent Polyarthritis and Hypercalcemia

Takeo Sato, Tsunehisa Tsuru, Kiyofumi Hagiwara, Kazuhisa Miyashita, Hiroaki Matsuno, Atsuo Goto, Masaru Oritsu, Teruhiko Hamanaka, Osamu Akiyama

Author information

Takeo Sato
Department of Allergy and Rheumatology, Japanese Red Cross Medical Center
Tsunehisa Tsuru
Department of Allergy and Rheumatology, Japanese Red Cross Medical Center
Kiyofumi Hagiwara
Department of Allergy and Rheumatology, Japanese Red Cross Medical Center
Kazuhisa Miyashita
Department of Nephrology, Japanese Red Cross Medical Center
Hiroaki Matsuno
Department of Allergy and Rheumatology, Japanese Red Cross Medical Center
Atsuo Goto
Department of Nephrology, Japanese Red Cross Medical Center
Masaru Oritsu
Department of Respiratory Medicine, Japanese Red Cross Medical Center
Teruhiko Hamanaka
Department of Ophthalmology, Japanese Red Cross Medical Center
Osamu Akiyama
Department of Allergy and Rheumatology, Japanese Red Cross Medical Center

Keywords: acute sarcoid arthritis, hypercalcemia, Löfgrens syndrome, prednisolone, sarcoidosis

JOURNAL OPEN ACCESS

2006 Volume 45 Issue 6 Pages 363-368

DOI https://doi.org/10.2169/internalmedicine.45.1521

Details

Abstract

A 45-year-old woman had bleary eyes and recurrent episodes of fever and arthritis in the knees and ankles. The patient had anterior uveitis, negative findings of the tuberculin test, and an increased serum lysozyme level, but bilateral hilar lymphadenopathy (BHL) was absent. During the course of her disease, the serum calcium and angiotensin-converting enzyme levels gradually increased to above the normal level, and the patient was clinically diagnosed as having sarcoidosis. The clinical features of arthritis were typical of those of Löfgrens syndrome although BHL and erythema nodosum were absent. The patient was successfully treated with 15 mg/day of prednisolone.

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