Moxibustion, an Alternative Therapy, Ameliorated Disturbed Circadian Rhythm of Plasma Arginine Vasopressin and Urine Output in Multiple System Atrophy

Ryuji Sakakibara; Eiko Murakami; Akira Katagiri; Sei Hayakawa; Tomoyuki Uchiyama; Tatsuya Yamamoto; Takamichi Hattori

doi:10.2169/internalmedicine.46.6450

CASE REPORTS

Moxibustion, an Alternative Therapy, Ameliorated Disturbed Circadian Rhythm of Plasma Arginine Vasopressin and Urine Output in Multiple System Atrophy

Ryuji Sakakibara, Eiko Murakami, Akira Katagiri, Sei Hayakawa, Tomoyuki Uchiyama, Tatsuya Yamamoto, Takamichi Hattori

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Keywords: multiple system atrophy, moxibustion, circadian rhythm, arginin vasopressin, nocturnal polyuria

JOURNAL OPEN ACCESS

2007 Volume 46 Issue 13 Pages 1015-1018

DOI https://doi.org/10.2169/internalmedicine.46.6450

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Abstract

Previously no alternative therapy approach has been made to ameliorate disturbed circadian arginin vasopressin rhythm (C-AVP-R) in multiple system atrophy (MSA). A 65-year-old man with MSA showed loss of C-AVP-R and nocturnal polyuria. We performed moxibustion at specific acupuncture points on the bladder and inside the feet, once a day, 3 times a week, for 6 months. After the treatment, his C-AVP-R appeared to be normal, and the nocturnal urine output decreased to 75% (p<0.01). Together with the previous studies, it seems possible that somatic warm stimulation by moxibustion in specific points might have facilitated AVP secretion in this patient.

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