Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Small Cell Carcinoma of the Extrahepatic Bile Duct Diagnosed with EUS-FNA and Effectively Treated with Chemoradiation
Norikazu ArakuraTakashi MurakiKenichi KomatsuYayoi OzakiHideaki HamanoEiji TanakaShigeyuki Kawa
Author information
JOURNAL OPEN ACCESS

2008 Volume 47 Issue 7 Pages 621-625

Details
Abstract

Small cell carcinoma of the bile duct system is extremely rare, and surgical procedures have been complicated by early hematogenous dissemination. In this study, we report a patient with small cell carcinoma of the bile duct system presenting with jaundice. The diagnosis was made early by endoscopic ultrasonography-guided fine needle aspiration biopsy (EUS-FNA). We performed radiation therapy of a total of 30 Gy, resulting in a marked decrease of serum neuron specific enolase levels and amelioration of jaundice, which had been resistant to drainage procedures. The patient was then treated with combined chemotherapy of cisplatin and CPT-11, which resulted in the disappearance of the tumor mass by image tests.

Content from these authors
© 2008 by The Japanese Society of Internal Medicine
Previous article Next article
feedback
Top