Platypnea-Orthodeoxia Syndrome: An Unusual Complication of Partial Liver Resection

Mohamad Alkhouli; Andrew Gagel; Moses Mathur; Brian O'Murchu

doi:10.2169/internalmedicine.54.3617

CASE REPORTS

Platypnea-Orthodeoxia Syndrome: An Unusual Complication of Partial Liver Resection

Mohamad Alkhouli, Andrew Gagel, Moses Mathur, Brian O'Murchu

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Keywords: liver resection, hepatoma, liver regeneration, platypnea-orthodeoxia, patent foramen ovale

JOURNAL OPEN ACCESS

2015 Volume 54 Issue 9 Pages 1067-1069

DOI https://doi.org/10.2169/internalmedicine.54.3617

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Abstract

Platypnea-orthodeoxia syndrome (POS) is a rare syndrome of severe hypoxemia upon assuming an upright position. It is classically described as shunting from the right atrium to the left atrium usually via a patent foramen ovale (PFO). Alterations in the intrathoracic anatomy after liver resection and regeneration may trigger this condition in patients with clinically silent PFO -a previously unreported cause of POS.

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