Radiation-induced Osteosarcoma of the Calvaria —Case Report—

Yasuo SUGITA; Minoru SHIGEMORI; Jun MIYAGI; Satoshi OCHIAI; Souichi LEE; Toshinori WATANABE; Hitoshi ABE; Minoru MORIMATSU

doi:10.2176/nmc.32.32

Yasuo SUGITA, Minoru SHIGEMORI, Jun MIYAGI, Satoshi OCHIAI, Souichi LEE, Toshinori WATANABE, Hitoshi ABE, Minoru MORIMATSU

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Keywords: acromegaly, computed tomography, magnetic resonance imaging, osteosarcoma, radiation-induced tumor

JOURNAL FREE ACCESS

1992 Volume 32 Issue 1 Pages 32-35

DOI https://doi.org/10.2176/nmc.32.32

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Abstract

The authors report a case of radiation-induced calvarial osteosarcoma. A 58-year-old female received subtotal removal of the pituitary adenoma and 5000 rads postoperative irradiation. Seven years later, an osteoblastic osteosarcoma occurred in the frontotemporal region. She received total tumor removal and chemotherapy. However, computed tomography subsequently revealed multiple small lesions at the margin of the bone flap. A chest x-ray film demonstrated lung metastasis. Local recurrence and lung metastasis require careful attention in radiation-induced osteosarcoma patients.

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