Mild Encephalitis/Encephalopathy With a Reversible Splenial Lesion: Evaluation by Diffusion Tensor Imaging —Three Case Reports—

Satoru OSUKA; Hironori IMAI; Eiichi ISHIKAWA; Akira MATSUSHITA; Tetsuya YAMAMOTO; Hiroki NOZUE; Tatsuyuki OHTO; Kousaku SAOTOME; Yoji KOMATSU; Akira MATSUMURA

doi:10.2176/nmc.50.1118

Case Reports

Mild Encephalitis/Encephalopathy With a Reversible Splenial Lesion: Evaluation by Diffusion Tensor Imaging

—Three Case Reports—

Satoru OSUKA, Hironori IMAI, Eiichi ISHIKAWA, Akira MATSUSHITA, Tetsuya YAMAMOTO, Hiroki NOZUE, Tatsuyuki OHTO, Kousaku SAOTOME, Yoji KOMATSU, Akira MATSUMURA

Author information

Satoru OSUKA
Department of Neurosurgery, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba
Research Fellow of the Japan Society for the Promotion of Science
Hironori IMAI
Department of Pediatrics, Tsukuba Medical Center Hospital
Eiichi ISHIKAWA
Department of Neurosurgery, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba
Akira MATSUSHITA
Department of Neurosurgery, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba
Tetsuya YAMAMOTO
Department of Neurosurgery, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba
Hiroki NOZUE
Department of Pediatrics, Tsukuba Medical Center Hospital
Tatsuyuki OHTO
Department of Pediatrics, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba
Kousaku SAOTOME
Department of Radiological Technology, Tsukuba Medical Center Hospital
Yoji KOMATSU
Department of Neurosurgery, Tsukuba Medical Center Hospital
Akira MATSUMURA
Department of Neurosurgery, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba

Keywords: diffusion tensor imaging, reversible splenial lesion, corpus callosum, encephalitis, encephalopathy

JOURNAL OPEN ACCESS

2010 Volume 50 Issue 12 Pages 1118-1122

DOI https://doi.org/10.2176/nmc.50.1118

Details

Abstract

Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a clinico-radiological syndrome with a very particular clinical course. Three patients with MERS were evaluated by various sequences of magnetic resonance imaging with diffusion tensor imaging. Initial diffusion-weighted imaging showed reduction in the apparent diffusion coefficient values in the lesions, which completely resolved with the elimination of symptoms. However, diffusion anisotropy of the lesions showed no remarkable abnormalities in the early or delayed phases. These results may indicate that white matter architecture is preserved in both early and delayed phases in MERS.

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