doiSerbia

Parcijalna resekcija slezine i spleno-renalni šant u lečenju portne hipertenzije sa splenomegalijom i hipersplenizmom

Radević Božina (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)
Ješić R. (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)
Sagić Dragan (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)
Perišić V. (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)
Nenezić D. (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)
Popov P. (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)
Ilijevski Nenad (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)
Dugalić V. (KCS - Institut za bolesti digestivnog sistema, Beograd)
Gajin P. (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)
Vučurević G. (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)
Radak Đorđe (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)
Trebješanin Z. (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)
Babić D. (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)
Kastratović D. (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)
Matić P. (Institut za kardiovaskularne bolesti 'Dedinje', Beograd)

Some of serious hepatic diseases with cirrhosis may be complicated by portal hypertension, splenomegaly and hypersplenism. Splenomegaly inhibits regenerative processes of the liver, and also intensifies sequestration of the cellular components of blood up to hypersplenism. Cytopenia caused by hypersplenism is aggravated by negative hepatic influence on bone marrow activity-hemathopoesis, and also by recurrent bleeding from oesophageal varices, and from the other site of gastrintestinal tract. This circle of pathologic conditions may be interrupted only by liver transplantation, until which patients are jeopardized by acute bleeding and chronic anemia. Partial resection of the spleen and splenorenal shunt may correct portal hypertension and hypersplenism, prevent gastrointestinal bleeding, and alleviate hepatic regenerative processes inhibition. In this study, 51 patients with partial resection of the spleen and splenorenal shunt, were analyzed.

Keywords: partial resection, spleen, portal hypertension, splenorenal shunt