Medicinski pregled 2011 Volume 64, Issue 7-8, Pages: 403-407
https://doi.org/10.2298/MPNS1108403M
Full text ( 223 KB)
Cited by
The incidence and risk factors of ventilator-associated pneumonia in patients with severe traumatic brain injury
Marjanović Vesna (Klinički centar Niš, Centar za anesteziju i reanimaciju, Niš)
Novak Vesna (Medicinski fakultet, Niš)
Veličković Ljubinka (Medicinski fakultet, Niš)
Marjanović Goran (Medicinski fakultet, Niš)
Introduction. Patients with severe traumatic brain injury are at a risk of
developing ventilator-associated pneumonia. The aim of this study was to
describe the incidence, etiology, risk factors for development of ventilator-
associated pneumonia and outcome in patients with severe traumatic brain
injury. Material and Methods. A retrospective study was done in 72 patients
with severe traumatic brain injury, who required mechanical ventilation for
more than 48 hours. Results. Ventilator-associated pneumonia was found in 31
of 72 (43.06%) patients with severe traumatic brain injury. The risk factors
for ventilator-associated pneumonia were: prolonged mechanical ventilation
(12.42 vs 4.34 days, p<0.001), longer stay at intensive care unit (17 vs 5
days, p<0.001) and chest injury (51.61 vs 19.51%, p< 0.009) compared to
patients without ventilator-associated pneumonia.. The mortality rate in the
patients with ventilator-associated pneumonia was higher (38.71 vs 21.95%,
p= 0.12). Conclusion. The development of ventilator-associated pneumonia in
patients with severe traumatic brain injury led to the increased morbidity
due to the prolonged mechanical ventilation, longer stay at intensive care
unit and chest injury, but had no effect on mortality.
Keywords: Respiration, Artificial + adverse effects, Pneumonia, Risk Factors, Brain Injuries, Incidence, Multiple Trauma
More data about this article available through SCIndeks