Vojnosanitetski pregled 2015 Volume 72, Issue 3, Pages: 233-240
https://doi.org/10.2298/VSP131202075M
Full text ( 695 KB)
Cited by
Influence of postoperative low-level laser therapy on the osseointegration of self-tapping implants in the posterior maxilla: A 6-week split-mouth clinical study
Mandić Borka (Faculty of Dentistry, Clinic of Oral Surgery, Belgrade)
Lazić Zoran (Military Medical Academy, Clinic of Dentistry, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade)
Marković Aleksa (Faculty of Dentistry, Clinic of Oral Surgery, Belgrade)
Mandić Bojan (Faculty of Dentistry, Clinic of Maxillofacial Surgery, Belgrade)
Mandić Miška (Faculty of Dentistry, Department of Orthodontics, Belgrade)
Đinić Ana (Faculty of Dentistry, Clinic of Oral Surgery, Belgrade)
Miličić Biljana (Faculty of Dentistry, Department for Medical Statistics and Informatics, Belgrade)
Background/Aim. Low-level laser therapy (LLLT) has been proven to stimulate
bone repair, affecting cellular proliferation, differentiation and adhesion,
and has shown a potential to reduce the healing time following implant
placement. The aim of this clinical study was to investigate the influence of
postoperative LLLT osseointegration and early success of self-tapping
implants placed into low-density bone. Methods. Following the split-mouth
design, self-tapping implants (n = 44) were inserted in the posterior maxilla
of 12 patients. One jaw side randomly received LLLT (test group), while the
other side was placebo (control group). For LLLT, a 637 nm
gallium-aluminum-arsenide (GaAlAs) laser (Medicolaser 637, Technoline,
Belgrade, Serbia) with an output power of 40 mW and continuous wave was used.
Low-level laser treatment was performed immediately after the surgery and
then repeated every day in the following 7 days. The total irradiation dose
per treatment was 6.26 J/cm² per implant. The study outcomes were: implant
stability, alkaline-phosphatase (ALP) activity and early implant success
rate. The follow-up took 6 weeks. Results. Irradiated implants achieved a
higher stability compared with controls during the entire follow-up and the
difference reached significance in the 5th postoperative week (paired t-test,
p = 0.030). The difference in ALP activity between the groups was
insignificant in any observation point (paired t-test, p > 0.05). The early
implant success rate was 100%, regardless of LLLT usage. Conclusion. LLLT
applied daily during the first postoperative week expressed no significant
influence on the osseointegration of selftapping implants placed into low
density bone of the posterior maxilla. Placement of self-tapping
macro-designed implants into low density bone could be a predictable
therapeutic procedure with a high early success rate regardless of LLLT
usage.
Keywords: dental implants, oral surgical procedures, laser therapy, low-level, bone regeneration, alkaline phosphatase, treatment outcome