Throat Infections are Associated with Exacerbation in a Substantial Proportion of Patients with Chronic Plaque Psoriasis
DOI:
https://doi.org/10.2340/00015555-2408Abstract
Streptococcal throat infections are known to trigger or exacerbate psoriasis, and several studies support the benefit of tonsillectomy. To evaluate the potential of tonsillectomy as a treatment, we used a retrospective study-specific questionnaire to assess the proportion of psoriasis patients with sore throat-associated psoriasis exacerbations. Our survey sampled 275 psoriasis patients. Of patients with plaque psoriasis, 42% reported sore throat-associated psoriasis exacerbations, and of patients with confirmed streptococcal infections, 72% reported aggravation. Notably, women and patients with early onset psoriasis were more likely to report psoriasis exacerbation after a sore throat (p<0.001, p=0.046, respectively). Other psoriasis aggravation factors were more common in patients with sore throat-associated exacerbations (p<0.01). Of tonsillectomized patients, 49% reported subsequent improvement and had more frequent sore throat-associated aggravation of psoriasis than patients who did not improve after tonsillectomy (p=0.015). These findings suggest a closer association between sore throats, streptococcal throat infections and plaque psoriasis than reported previously.Downloads
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Copyright (c) 2016 Ragna H. Thorleifsdottir, Jenna Eysteinsdóttir, Jón H. Olafsson, Martin I Sigurdsson, Andrew Johnston, Helgi Valdimarsson, Bardur Sigurgeirsson
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